Cadherin 16 è un gene codificato dal simbolo CDH16. Altri nomi includono: Cadherin-16; Kidney-specific cadherin; Ksp-cadherin; CDH16. Cadherin 16 ha una massa di 89.92kDa e una lunghezza di amminoacidi di 829.
Offriamo 32 anticorpi contro Cadherin 16, allevati nel Coniglio e Topo, che sono adatti per WB, IHC, ELISA, ICC/IF e Citometria a Flusso con campioni derivati da Umano, Topo, Ratto, Coniglio e Cane.
Informazioni su geni e proteine
Riepilogo UniProt
Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.
Sommario di Entrez
This gene is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. Mapped to a previously identified cluster of cadherin genes on chromosome 16q22.1, the gene localizes with superfamily members CDH1, CDH3, CDH5, CDH8 and CDH11. The protein consists of an extracellular domain containing 6 cadherin domains, a transmembrane region and a truncated cytoplasmic domain but lacks the prosequence and tripeptide HAV adhesion recognition sequence typical of most classical cadherins. Expression is exclusively in kidney, where the protein functions as the principal mediator of homotypic cellular recognition, playing a role in the morphogenic direction of tissue development. Alternatively spliced transcript variants encoding distinct isoforms have been identified.
Specificità del tessuto
Kidney specific.
Posizione cellulare
Cell membrane.
