c-Myb è un gene codificato dal simbolo MYB. Altri nomi includono: Transcriptional activator Myb; Proto-oncogene MYB. c-Myb ha una massa di 72.34kDa e una lunghezza di amminoacidi di 640.
Offriamo 10 anticorpi contro c-Myb, allevati nel Coniglio, Topo e Capra, che sono adatti per WB, IHC, ELISA e ICC/IF con campioni derivati da Umano, Topo e Ratto.
Informazioni su geni e proteine
Riepilogo UniProt
Transcriptional activator; DNA-binding protein that specifically recognize the sequence 5'-YAAC[GT]G-3'. Plays an important role in the control of proliferation and differentiation of hematopoietic progenitor cells.
Sommario di Entrez
This gene encodes a protein with three HTH DNA-binding domains that functions as a transcription regulator. This protein plays an essential role in the regulation of hematopoiesis. This gene may be aberrently expressed or rearranged or undergo translocation in leukemias and lymphomas, and is considered to be an oncogene. Alternative splicing results in multiple transcript variants.
Modifica post-translazionale
Ubiquitinated; mediated by SIAH1 and leading to its subsequent proteasomal degradation.
Posizione cellulare
Nucleus.
