Bone marrow stromal cell antigen 1 è un gene codificato dal simbolo BST1. Altri nomi includono: ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2; ADP-ribosyl cyclase 2; Bone marrow stromal antigen 1; BST-1; Cyclic ADP-ribose hydrolase 2; cADPr hydrolase 2; BST1. Bone marrow stromal cell antigen 1 ha una massa di 35.72kDa e una lunghezza di amminoacidi di 318.
Offriamo 14 anticorpi contro Bone marrow stromal cell antigen 1, allevati nel Coniglio e Topo, che sono adatti per WB, IHC, ELISA, ICC/IF, Citometria a Flusso e IP con campioni derivati da Umano, Topo, Ratto e Primati.
Informazioni su geni e proteine
Riepilogo UniProt
Synthesizes the second messengers cyclic ADP-ribose and nicotinate-adenine dinucleotide phosphate, the former a second messenger that elicits calcium release from intracellular stores. May be involved in pre-B-cell growth.
Sommario di Entrez
Bone marrow stromal cell antigen-1 is a stromal cell line-derived glycosylphosphatidylinositol-anchored molecule that facilitates pre-B-cell growth. The deduced amino acid sequence exhibits 33% similarity with CD38. BST1 expression is enhanced in bone marrow stromal cell lines derived from patients with rheumatoid arthritis. The polyclonal B-cell abnormalities in rheumatoid arthritis may be, at least in part, attributed to BST1 overexpression in the stromal cell population.
Specificità del tessuto
Widely expressed.
Somiglianze di sequenza
Belongs to the ADP-ribosyl cyclase family.
Posizione cellulare
Cell membrane.
