BMP6 è un gene codificato dal simbolo BMP6. Altri nomi includono: Bone morphogenetic protein 6; BMP-6; VG-1-related protein; VG-1-R; VGR. BMP6 ha una massa di 57.23kDa e una lunghezza di amminoacidi di 513.
Offriamo 6 anticorpi contro BMP6, allevati nel Coniglio, che sono adatti per WB, IHC, ELISA e ICC/IF con campioni derivati da Umano, Topo e Ratto.
Informazioni su geni e proteine
Riepilogo UniProt
Induces cartilage and bone formation.
Sommario di Entrez
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein regulates a wide range of biological processes including iron homeostasis, fat and bone development, and ovulation. Differential expression of this gene may be associated with progression of breast and prostate cancer. Mutations in this gene may be associated with iron overload in human patients.
Somiglianze di sequenza
Belongs to the TGF-beta family.
Posizione cellulare
Secreted.
