Blood Group H2 antigen è un gene codificato dal simbolo ABO. Altri nomi includono: Histo-blood group ABO system transferase; Fucosylglycoprotein 3-alpha-galactosyltransferase; Fucosylglycoprotein alpha-N-acetylgalactosaminyltransferase; Glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase; Glycoprotein-fucosylgalactoside alpha-galactosyltransferase; Histo-blood group A transferase; A transferase; Histo-blood group B transferase; B transferase; NAGAT; ABO. Blood Group H2 antigen ha una massa di 40.93kDa e una lunghezza di amminoacidi di 354.
Offriamo 10 anticorpi contro Blood Group H2 antigen, allevati nel Coniglio e Topo, che sono adatti per WB, IHC, ICC/IF e Citometria a Flusso con campioni derivati da Umano, Topo, Ratto e Maiale.
Informazioni su geni e proteine
Riepilogo UniProt
This protein is the basis of the ABO blood group system. The histo-blood group ABO involves three carbohydrate antigens: A, B, and H. A, B, and AB individuals express a glycosyltransferase activity that converts the H antigen to the A antigen (by addition of UDP-GalNAc) or to the B antigen (by addition of UDP-Gal), whereas O individuals lack such activity.
Sommario di Entrez
This gene encodes proteins related to the first discovered blood group system, ABO. Which allele is present in an individual determines the blood group. The 'O' blood group is caused by a deletion of guanine-258 near the N-terminus of the protein which results in a frameshift and translation of an almost entirely different protein. Individuals with the A, B, and AB alleles express glycosyltransferase activities that convert the H antigen into the A or B antigen. Other minor alleles have been found for this gene.
Somiglianze di sequenza
Belongs to the glycosyltransferase 6 family.
Modifica post-translazionale
The soluble form derives from the membrane form by proteolytic processing.
Posizione cellulare
Golgi apparatus > Golgi stack membrane. Secreted.
Membrane-bound form in trans cisternae of Golgi. Secreted into the body fluid.
