Anticorpi B7H4

15 prodotti

B7H4 è un gene codificato dal simbolo VTCN1. Altri nomi includono: V-set domain-containing T-cell activation inhibitor 1; B7 homolog 4; B7-H4; B7h.5; Immune costimulatory protein B7-H4; Protein B7S1; T-cell costimulatory molecule B7x; VTCN1. B7H4 ha una massa di 30.88kDa e una lunghezza di amminoacidi di 282.

Offriamo 15 anticorpi contro B7H4, allevati nel Coniglio, Topo, Capra e Human, che sono adatti per WB, IHC, ELISA, ICC/IF e Citometria a Flusso con campioni derivati ​​da Umano, Topo e Ratto.

Informazioni su geni e proteine

Riepilogo UniProt
Negatively regulates T-cell-mediated immune response by inhibiting T-cell activation, proliferation, cytokine production and development of cytotoxicity. When expressed on the cell surface of tumor macrophages, plays an important role, together with regulatory T-cells (Treg), in the suppression of tumor-associated antigen-specific T-cell immunity. Involved in promoting epithelial cell transformation.
Sommario di Entrez
This gene encodes a protein belonging to the B7 costimulatory protein family. Proteins in this family are present on the surface of antigen-presenting cells and interact with ligand bound to receptors on the surface of T cells. Studies have shown that high levels of the encoded protein has been correlated with tumor progression. A pseudogene of this gene is located on chromosome 20. Multiple transcript variants encoding different isoforms have been found for this gene.
Specificità del tessuto
Overexpressed in breast, ovarian, endometrial, renal cell (RCC) and non-small-cell lung cancers (NSCLC). Expressed on activated T- and B-cells, monocytes and dendritic cells, but not expressed in most normal tissues (at protein level). Widely expressed, including in kidney, liver, lung, ovary, placenta, spleen and testis.
Somiglianze di sequenza
Belongs to the immunoglobulin superfamily. BTN/MOG family.
Modifica post-translazionale
N-glycosylated.
Posizione cellulare
Cell membrane.

Expressed at the cell surface. A soluble form has also been detected.
Flow Cytometry - Anti-B7H4 Antibody [B7H4/1788] (A250376) - Antibodies.com
(5)
Flow Cytometry - Anti-B7H4 Antibody [B7H4/1788] - BSA and Azide free (A253556) - Antibodies.com
(5)
SDS-PAGE - Alsevalimab Biosimilar - Anti-B7H4 Antibody - Low endotoxin, Azide free (A323275) - Antibodies.com
(3)
Visualizza prodottoAnticorpo ricombinante
Flow Cytometry - Anti-B7H4 Antibody [B7H4/2652R] - BSA and Azide free (A253557) - Antibodies.com
(4)
Visualizza prodottoAnticorpo ricombinante
Western Blot - Anti-B7H4 Antibody (A84379) - Antibodies.com
(3)
Flow Cytometry - Anti-B7H4 Antibody [B7H4/2652R] (A250377) - Antibodies.com
(4)
Visualizza prodottoAnticorpo ricombinante
SDS-PAGE - Anti-B7H4 Antibody [Research Grade Biosimilar] - Low endotoxin, Azide free (A323888) - Antibodies.com
(3)
Visualizza prodottoAnticorpo ricombinante
ELISA - AZD-8205 Biosimilar - Anti-B7H4 Antibody - BSA and Azide free (A324622) - Antibodies.com
(2)
Visualizza prodottoAnticorpo ricombinante
ELISA - XMT-1660 Biosimilar - Anti-B7H4 Antibody - BSA and Azide free (A324851) - Antibodies.com
(2)
Visualizza prodottoAnticorpo ricombinante
Western Blot - Anti-B7H4 Antibody (A12928) - Antibodies.com
ELISA - Anti-B7H4 Antibody [Alsevalimab Biosimilar] - Azide free (A318884) - Antibodies.com
(2)
Visualizza prodottoAnticorpo ricombinante
Flow Cytometry - SGN-B7H4V Biosimilar - Anti-B7H4 Antibody - BSA and Azide free (A324691) - Antibodies.com
Visualizza prodottoAnticorpo ricombinante
Western Blot - Anti-B7H4 Antibody (A85015) - Antibodies.com
Immunohistochemistry - Anti-B7H4 Antibody [IHC104] (A324385) - Antibodies.com
Immunohistochemistry - VTCN1 Antibody from Signalway Antibody (36273) - Antibodies.com
(2)

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