Annexin VI è un gene codificato dal simbolo ANXA6. Altri nomi includono: Annexin A6; 67 kDa calelectrin; Annexin-6; Calphobindin-II; CPB-II; Chromobindin-20; Lipocortin VI; Protein III; p68; p70; ANXA6; ANX6. Annexin VI ha una massa di 75.87kDa e una lunghezza di amminoacidi di 673.
Offriamo 14 anticorpi contro Annexin VI, allevati nel Coniglio e Topo, che sono adatti per WB, IHC, ELISA e ICC/IF con campioni derivati da Umano, Topo, Ratto e Scimmia.
Informazioni su geni e proteine
Riepilogo UniProt
May associate with CD21. May regulate the release of Ca(2+) from intracellular stores.
Sommario di Entrez
Annexin VI belongs to a family of calcium-dependent membrane and phospholipid binding proteins. Several members of the annexin family have been implicated in membrane-related events along exocytotic and endocytotic pathways. The annexin VI gene is approximately 60 kbp long and contains 26 exons. It encodes a protein of about 68 kDa that consists of eight 68-amino acid repeats separated by linking sequences of variable lengths. It is highly similar to human annexins I and II sequences, each of which contain four such repeats. Annexin VI has been implicated in mediating the endosome aggregation and vesicle fusion in secreting epithelia during exocytosis. Alternatively spliced transcript variants have been described.
Somiglianze di sequenza
Belongs to the annexin family.
Modifica post-translazionale
Phosphorylated in response to growth factor stimulation.
Posizione cellulare
Cytoplasm. Melanosome.
Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
