ADFP è un gene codificato dal simbolo PLIN2. Altri nomi includono: Perilipin-2; Adipophilin; Adipose differentiation-related protein; ADRP; PLIN2. ADFP ha una massa di 48.08kDa e una lunghezza di amminoacidi di 437.
Offriamo 17 anticorpi contro ADFP, allevati nel Coniglio e Topo, che sono adatti per WB, IHC, ELISA, ICC/IF e Citometria a Flusso con campioni derivati da Umano, Topo e Ratto.
Informazioni su geni e proteine
Riepilogo UniProt
May be involved in development and maintenance of adipose tissue.
Sommario di Entrez
The protein encoded by this gene belongs to the perilipin family, members of which coat intracellular lipid storage droplets. This protein is associated with the lipid globule surface membrane material, and maybe involved in development and maintenance of adipose tissue. However, it is not restricted to adipocytes as previously thought, but is found in a wide range of cultured cell lines, including fibroblasts, endothelial and epithelial cells, and tissues, such as lactating mammary gland, adrenal cortex, Sertoli and Leydig cells, and hepatocytes in alcoholic liver cirrhosis, suggesting that it may serve as a marker of lipid accumulation in diverse cell types and diseases. Alternatively spliced transcript variants have been found for this gene.
Specificità del tessuto
Milk lipid globules.
Somiglianze di sequenza
Belongs to the perilipin family.
Modifica post-translazionale
Acylated; primarily with C14, C16 and C18 fatty acids.
Posizione cellulare
Membrane. Lipid droplet.
