Uroguanylin è un gene codificato dal simbolo GUCA2B. È noto anche come: Guanylate cyclase activator 2B; GUCA2B. Uroguanylin ha una massa di 12.07kDa e una lunghezza di amminoacidi di 112.
Offriamo 2 Uroguanylin ELISA kit per il rilevamento qualitativo o quantitativo di Uroguanylin da campioni di Umano.
Informazioni su geni e proteine
Riepilogo UniProt
Endogenous activator of intestinal guanylate cyclase. It stimulates this enzyme through the same receptor binding region as the heat-stable enterotoxins. May be a potent physiological regulator of intestinal fluid and electrolyte transport. May be an autocrine/paracrine regulator of intestinal salt and water transport.
Sommario di Entrez
This gene encodes a preproprotein that is proteolytically processed to generate multiple protein products, including uroguanylin, a member of the guanylin family of peptides and an endogenous ligand of the guanylate cyclase-C receptor. Binding of this peptide to its cognate receptor stimulates an increase in cyclic GMP and may regulate salt and water homeostasis in the intestine and kidneys.
Specificità del tessuto
Stomach and intestine.
Somiglianze di sequenza
Belongs to the guanylin family.
Posizione cellulare
Secreted.
