MCP3 è un gene codificato dal simbolo CCL7. Comunemente indicato anche come: C-C motif chemokine 7; Monocyte chemoattractant protein 3; Monocyte chemotactic protein 3; MCP-3; NC28; Small-inducible cytokine A7; CCL7; SCYA6; SCYA7. MCP3 ha una massa di 11.2kDa e una lunghezza di amminoacidi di 99.
Offriamo 14 MCP3 ELISA kit per il rilevamento qualitativo o quantitativo di MCP3 da campioni di Umano, Topo e Ratto.
Informazioni su geni e proteine
Riepilogo UniProt
Chemotactic factor that attracts monocytes and eosinophils, but not neutrophils. Augments monocyte anti-tumor activity. Also induces the release of gelatinase B. This protein can bind heparin. Binds to CCR1, CCR2 and CCR3.
Sommario di Entrez
This gene encodes monocyte chemotactic protein 3, a secreted chemokine which attracts macrophages during inflammation and metastasis. It is a member of the C-C subfamily of chemokines which are characterized by having two adjacent cysteine residues. The protein is an in vivo substrate of matrix metalloproteinase 2, an enzyme which degrades components of the extracellular matrix. This gene is part of a cluster of C-C chemokine family members on chromosome 17q.
Somiglianze di sequenza
Belongs to the intercrine beta (chemokine CC) family.
Modifica post-translazionale
O-glycosylated.
Posizione cellulare
Secreted.
