GRO beta è un gene codificato dal simbolo CXCL2. Comunemente indicato anche come: C-X-C motif chemokine 2; Growth-regulated protein beta; Gro-beta; Macrophage inflammatory protein 2-alpha; MIP2-alpha; CXCL2; GRO2; GROB; MIP2A; SCYB2. GRO beta ha una massa di 11.39kDa e una lunghezza di amminoacidi di 107.
Offriamo 2 GRO beta ELISA kit per il rilevamento qualitativo o quantitativo di GRO beta da campioni di Umano.
Informazioni su geni e proteine
Riepilogo UniProt
Produced by activated monocytes and neutrophils and expressed at sites of inflammation. Hematoregulatory chemokine, which, in vitro, suppresses hematopoietic progenitor cell proliferation. GRO-beta(5-73) shows a highly enhanced hematopoietic activity.
Sommario di Entrez
This antimicrobial gene is part of a chemokine superfamily that encodes secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CXC subfamily, is expressed at sites of inflammation and may suppress hematopoietic progenitor cell proliferation.
Somiglianze di sequenza
Belongs to the intercrine alpha (chemokine CxC) family.
Modifica post-translazionale
The N-terminal processed form GRO-beta(5-73) is produced by proteolytic cleavage after secretion from bone marrow stromal cells.
Posizione cellulare
Secreted.
