Fatty Acid Synthase è un gene codificato dal simbolo FASN. Altri nomi includono: FASN; FAS. Fatty Acid Synthase ha una massa di 273.43kDa e una lunghezza di amminoacidi di 2511.
Offriamo 10 Fatty Acid Synthase ELISA kit per il rilevamento qualitativo o quantitativo di Fatty Acid Synthase da campioni di Umano, Topo, Ratto, Coniglio e Pollo.
Informazioni su geni e proteine
Riepilogo UniProt
Fatty acid synthetase catalyzes the formation of long-chain fatty acids from acetyl-CoA, malonyl-CoA and NADPH. This multifunctional protein has 7 catalytic activities as an acyl carrier protein.
Sommario di Entrez
The enzyme encoded by this gene is a multifunctional protein. Its main function is to catalyze the synthesis of palmitate from acetyl-CoA and malonyl-CoA, in the presence of NADPH, into long-chain saturated fatty acids. In some cancer cell lines, this protein has been found to be fused with estrogen receptor-alpha (ER-alpha), in which the N-terminus of FAS is fused in-frame with the C-terminus of ER-alpha.
Specificità del tessuto
Ubiquitous. Prominent expression in brain, lung, and liver.
Posizione cellulare
Cytoplasm. Melanosome.
Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
