beta Defensin 3 è un gene codificato dal simbolo DEFB103A. Altri nomi includono: Beta-defensin 103; Beta-defensin 3; BD-3; Defensin, beta 103; Defensin-like protein; DEFB103A; BD3; DEFB103; DEFB3. beta Defensin 3 ha una massa di 7.7kDa e una lunghezza di amminoacidi di 67.
Offriamo 9 beta Defensin 3 ELISA kit per il rilevamento qualitativo o quantitativo di beta Defensin 3 da campioni di Umano, Topo e Bovino.
Informazioni su geni e proteine
Riepilogo UniProt
Exhibits antimicrobial activity against Gram-positive bacteria S.aureus and S.pyogenes, Gram-negative bacteria P.aeruginosa and E.coli and the yeast C.albicans. Kills multiresistant S.aureus and vancomycin-resistant E.faecium. No significant hemolytic activity was observed.
Sommario di Entrez
Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Members of the defensin family are highly similar in protein sequence. This gene encodes defensin, beta 103, an antibiotic peptide which is induced by bacteria and interferon gamma, and which displays antimicrobial activity against S. aureus, S. pyogenes, P. aeruginosa, E. coli, and C. albicans.
Specificità del tessuto
Highly expressed in skin and tonsils, and to a lesser extent in trachea, uterus, kidney, thymus, adenoid, pharynx and tongue. Low expression in salivary gland, bone marrow, colon, stomach, polyp and larynx. No expression in small intestine.
Somiglianze di sequenza
Belongs to the beta-defensin family.
Posizione cellulare
Secreted.
