Anti-PI 3 Kinase p110 delta Anticorpo (A283225)

Anti-PI 3 Kinase p110 delta Antibody

Rabbit polyclonal antibody to PI 3 Kinase p110 delta.

This antibody recognises an epitope within the C-terminal (CT) region of human PI3-kinase p110 subunit delta (Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta), a member of the PI3/PI4-kinase family of lipid kinases, implicated in the regulation of signal transduction during cell growth.PI3-kinase is a heterodimer consisting of a p85 regulatory subunit and a p110 catalytic subunit, which itself is divided into isoforms p110alpha, p110beta, p110delta and p110gamma.Expression of p110delta is predominantly restricted to leucocytes, exhibits a broad phosphoinositide lipid substrate specificity, and binds to Ras-GTP and p85.Rabbit anti Human PI-3 kinase subunit Delta is suitable for use in immunocytochemistry.

WB, ELISA

ELISA: 1:75,000, WB: 1:3,000

Human

Synthetic peptide sequence SWKTKVNWLAHNVSKDNRQ with added cysteine, corresponding to amino acids 1026-1044 within the C-terminus of human PI3-Kinase p110 subunit delta.

SWKTKVNWLAHNVSKDNRQ

Rabbit

Polyclonal

IgG

Unconjugated

1 mg/ml

Supplied in Phosphate Buffered Saline with 0.1% BSA and <0.1% Sodium Azide.

Store undiluted at -20°C only. Storage in frost free freezers is not recommended. Avoid freeze-thaw cycles. Should this product contain a precipitate we recommend microcentrifugation before use.

Rabbit anti Human PI-3 kinase subunit Delta recognizes an epitope within the C-terminal (CT) region of human PI3-kinase p110 subunit delta (Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta), a member of the PI3/PI4-kinase family of lipid kinases, implicated in the regulation of signal transduction during cell growth.PI3-kinase is a heterodimer consisting of a p85 regulatory subunit and a p110 catalytic subunit, which itself is divided into isoforms p110alpha, p110beta, p110delta and p110gamma.Expression of p110delta is predominantly restricted to leucocytes, exhibits a broad phosphoinositide lipid substrate specificity, and binds to Ras-GTP and p85.Rabbit anti Human PI-3 kinase subunit Delta is suitable for use in immunocytochemistry.

5-bisphosphate 3-kinase 110 kDa catalytic subunit delta, 5-bisphosphate 3-kinase catalytic subunit delta isoform, APDS, GRB1, IMD14, p110d, p110delta, p110dp85a, p85-ALPHA, Phosphatidylinositol 3 kinase catalytic delta polypeptide, Phosphatidylinositol 4 5 bisphosphate 3 kinase catalytic subunit delta isoform, Phosphatidylinositol 4,5 bisphosphate 3 kinase 110 kDa catalytic subunit delta, Phosphatidylinositol 4,5 bisphosphate 3 kinase, catalytic subunit delta, Phosphatidylinositol 45 bisphosphate 3 kinase catalytic subunit delta isoform, Phosphatidylinositol-4, Phosphoinositide 3 kinase B, Phosphoinositide 3 kinase C, Phosphoinositide 3 kinase catalytic delta polypeptide, Phosphoinositide 3 kinase, catalytic, delta polypeptide variant p37delta, PI3 kinase p110 subunit delta, PI3-kinase subunit delta, PI3K, PI3K-delta, PI3Kdelta, Pik3cd, PIK3R1, PK3CD, PK3CD_HUMAN, PtdIns 3 kinase p110, PtdIns 3 kinase subunit p110 delta, PtdIns-3-kinase subunit delta, PtdIns-3-kinase subunit p110-delta