Anti-PDPK1 (phospho Ser241) Anticorpo (A283667)

Anti-PDPK1 (phospho Ser241) Antibody

Rabbit polyclonal antibody to PDPK1 (phospho Ser241).

This antibody recognises PDK1, also known as 3-phosphoinositide-dependent protein kinase 1 or PDPK1, when phosphorylated at serine 241. PDK1 is a master kinase involved in numerous cell processes including proliferation, differentiation and cell survival. PDK1 is crucial for the activation of AKT/PKB and many other AGC kinases including PKC, S6K, SGK.Autophosphorylation of serine 241 is required for PDK1 activity.

WB, IHC-P

IHC-P: 1:50 - 1:100, WB: 1:500 - 1:2,000

Human, Mouse, Rat

Phospho-specific peptide corresponding to residues surrounding Ser241 of human PDK1.

Rabbit

Polyclonal

IgG

Unconjugated

Liquid

Supplied in Phosphate Buffered Saline with 50% Glycerol and 0.02% Sodium Azide.

Store undiluted at -20°C. Storage in frost free freezers is not recommended. Avoid freeze-thaw cycles. Should this product contain a precipitate we recommend microcentrifugation before use.

Rabbit anti PDK1 (pSer241) antibody recognizes PDK1, also known as 3-phosphoinositide-dependent protein kinase 1 or PDPK1, when phosphorylated at serine 241. PDK1 is a master kinase involved in numerous cell processes including proliferation, differentiation and cell survival. PDK1 is crucial for the activation of AKT/PKB and many other AGC kinases including PKC, S6K, SGK.Autophosphorylation of serine 241 is required for PDK1 activity (Wang et al. 2017).

3 phosphoinositide dependent protein kinase 1, 3-phosphoinositide-dependent protein kinase 1, hPDK 1, hPDK1, MGC20087, MGC35290, OTTHUMP00000159109, OTTHUMP00000159110, OTTHUMP00000174525, PDK1, PDPK1_HUMAN, PDPK2, PDPK2P, PkB kinase, PkB kinase like gene 1, PkB like 1, PRO0461, Protein kinase