Anti-PAX8 Anticorpo [PAX8/1492] (A250361)

Anticorpo monoclonale [PAX8/1492] di topo contro PAX8 per Flow Cytometry, IF, WB e IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Spese di spedizione
Tempi di consegna
4-6 Giorni lavorativi
Telefono
+1 (314) 370-6046
Lun - Ven, 8:00 - 16:00 AST
E-mail
orders@antibodies.com
Nome
Anti-PAX8 Antibody [PAX8/1492]
Descrizione
Mouse monoclonal [PAX8/1492] antibody to PAX8.
Specificità
This antibody recognizes a protein of 62kDa, identified as PAX8. It is a member of the paired box (PAX) family of transcription factors. This nuclear protein is involved in thyroid follicular cell development and expression of thyroid-specific genes. Mutations in this gene have been associated with thyroid dysgenesis, thyroid follicular carcinomas, and atypical thyroid adenomas. PAX-8 is expressed in the thyroid (and associated carcinomas), non-ciliated mucosal cells of the fallopian tubes, and simple ovarian inclusion cysts, but not normal ovarian surface epithelial cells. PAX-8 is expressed in a high percentage of ovarian serous, endometrioid, and clear cell carcinomas, but only rarely in primary ovarian mucinous adenocarcinomas. PAX-8 expression is reported in renal tubules as well as renal cell carcinoma, nephroblastoma, and seminoma. PAX-8 antibody may be used as an additional immunohistochemical marker for renal epithelial tumors.
Applicazioni
Flow Cytometry, IF, WB, IHC-P
Diluizioni consigliate
Flow Cytometry: 1-2 µg/million cells, IF: 1-2 µg/ml, WB: 1-2 µg/ml, IHC-P: 1-2 µg/ml
Reattività
Human
Immunogeno
Recombinant fragment, around amino acids 60-261, of human PAX8 protein. The exact sequence is proprietary.
Specie ospite
Mouse
Clonalità
Monoclonal
Clona ID
PAX8/1492
Isotipo
IgG2b
Catene leggere
kappa
Coniugare

Unconjugated

Purificazione
Protein A/G chromatography.
Concentrazione
200 µg/ml
Peso molecolare
62 kDa
Forma del prodotto
Liquid
Formulazione
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Conservazione
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Note generali
This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-PAX8 Antibody [PAX8/1492] - BSA and Azide free (A253541).
Sinonimi
OTTHUMP00000158659, OTTHUMP00000158660, OTTHUMP00000203723, OTTHUMP00000203724, Paired box 8, Paired box gene 8, paired box homeotic gene 8, Paired box protein Pax 8, Paired box protein Pax-8, Paired domain gene 8, PAX 8, PAX8_HUMAN
Dichiarazione di non responsabilità
Questo prodotto è solo per uso di ricerca. Non è inteso per uso diagnostico o terapeutico.

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