Ricombinante Anti-PAX6 Anticorpo [PAX6/8578R] (A315473)

$765

Anticorpo monoclonale [PAX6/8578R] di coniglio contro PAX6 per IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Spese di spedizione
Tempi di consegna
4-6 Giorni lavorativi
Telefono
+1 (314) 370-6046
Lun - Ven, 8:00 - 16:00 AST
E-mail
orders@antibodies.com
Nome
Anti-PAX6 Antibody [PAX6/8578R]
Descrizione
Recombinant rabbit monoclonal [PAX6/8578R] antibody to PAX6.
Specificità
Pax genes contain paired domains with strong homology to genes in Drosophila, which are involved in programming early development. Lesions in the Pax-6 gene account for most cases of aniridia, a congenital malformation of the eye, chiefly characterized by iris hypoplasia, which can cause blindness. Pax-6 is involved in other anterior segment malformations besides aniridia, such as Peters anomaly, a major error in the embryonic development of the eye with corneal clouding with variable iridolenticulocorneal adhesions. The Pax-6 gene encodes a transcriptional regulator that recognizes target genes through its paired-type DNA-binding domain. The paired domain is composed of two distinct DNA-binding subdomains, the amino-terminal subdomain and the carboxy-terminal subdomain, which bind respective consensus DNA sequences. The human Pax-6 gene produces two alternatively spliced isoforms that have the distinct structure of the paired domain.
Applicazioni
IHC-P
Controllo positivo
Human pancreas or cerebellum.
Diluizioni consigliate
IHC: 1-2 µg/ml
Reattività
Human
Immunogeno
Recombinant fragment (N-terminus; aa 1-300) of human PAX6 protein.
Specie ospite
Rabbit
Clonalità
Monoclonal
Clona ID
PAX6/8578R
Isotipo
IgG
Catene leggere
kappa
Coniugare

Unconjugated

Purificazione
Protein A/G chromatography.
Concentrazione
200 µg/ml
Peso molecolare
47 kDa
Forma del prodotto
Liquid
Formulazione
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Conservazione
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Sinonimi
AN, AN 2, AN2, Aniridia type II protein, D11S812E, FVH1, KIAA0552, Leucine zipper putative tumor suppressor 3, LZTS3, MGC17209, MGDA, Oculorhombin, Paired box 6, Paired Box Gene 6, Paired box gene 6 (aniridia keratitis), Paired box homeotic gene 6, Paired box protein Pax-6, Paired box protein Pax6, PAX 6, PAX6_HUMAN, ProSAP-interacting protein 1, PROSAPIP1, Sey, WAGR
Dichiarazione di non responsabilità
Questo prodotto è solo per uso di ricerca. Non è inteso per uso diagnostico o terapeutico.

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