Anti-PAX3 Anticorpo [PAX3/8426] (A315467)

$765

Anticorpo monoclonale [PAX3/8426] di topo contro PAX3 per IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Spese di spedizione
Tempi di consegna
4-6 Giorni lavorativi
Telefono
+1 (314) 370-6046
Lun - Ven, 8:00 - 16:00 AST
E-mail
orders@antibodies.com
Nome
Anti-PAX3 Antibody [PAX3/8426]
Descrizione
Mouse monoclonal [PAX3/8426] antibody to PAX3.
Specificità
Pax genes contain paired domains that share strong homology to genes in Drosophila which are involved in programming early development. The product of the PAX3 gene is a DNA-binding protein expressed during early neurogenesis. Pax-3 is a protein containing both a paired domain and a paired-type homeodomain. During early neurogenesis, Pax-3 expression is limited to mitotic cells in the ventricular zone of the developing spinal cord and to distinct regions in the hindbrain, midbrain and diencephalon. In 10-12 day embryos, expression of Pax-3 is also seen in neural crest cells of the developing spinal ganglia, the craniofacial mesectoderm and in limb mesenchyme. Mutations in the MITF and Pax-3 genes, encoding transcription factors, are responsible for Waardenburg syndrome II (WSII) and WSI/WSIII, respectively.
Applicazioni
IHC-P
Controllo positivo
Human skin and skeletal muscle tissue.
Diluizioni consigliate
IHC: 1-2 µg/ml
Reattività
Human
Immunogeno
Recombinant fragment (around Amino Acids 150-350) of human PAX3 protein. The exact sequence is proprietary.
Specie ospite
Mouse
Clonalità
Monoclonal
Clona ID
PAX3/8426
Isotipo
IgG1
Catene leggere
kappa
Coniugare

Unconjugated

Purificazione
Protein A/G chromatography.
Concentrazione
200 µg/ml
Peso molecolare
56 kDa
Forma del prodotto
Liquid
Formulazione
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Conservazione
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Sinonimi
CDHS, HUP 2, HUP2, MGC120381, MGC120382, MGC120383, MGC120384, MGC134778, Paired box 3, Paired box gene 3, Paired box homeotic gene 3, Paired box protein Pax 3, Paired box protein Pax-3, Paired box protein Pax3, Paired domain gene 3, Paired domain gene HuP2, PAX 3, PAX3/FKHR fusion gene, PAX3_HUMAN, Sp, splotch, Waardenburg syndrome 1, WS 1, WS1, WS3
Dichiarazione di non responsabilità
Questo prodotto è solo per uso di ricerca. Non è inteso per uso diagnostico o terapeutico.

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