Ricombinante Anti-p63 Anticorpo [TP63/4379R] (A278082)

Name: Anti-p63 Antibody [TP63/4379R]
Brand: Antibodies.com
SKU: A278082
Price: 525.0 USD
Availability: InStock

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$525

Anticorpo monoclonale [TP63/4379R] di coniglio contro p63 per IHC-P.

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Alternative Formats and ConjugatesAlternative Formats

Carrier Free and Preservative Free

Consegna

Spese di spedizione

$40

Tempi di consegna

4-6 Giorni lavorativi

Contattaci

Telefono

+1 (314) 370-6046

E-mail

orders@antibodies.com

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Tag dei prodotti:

Anticorpo Monospecifico Anticorpo Ricombinante

Descrizione Prodotto

Nome

Anti-p63 Antibody [TP63/4379R]

Descrizione

Recombinant rabbit monoclonal [TP63/4379R] antibody to p63.

Specificità

p63 is a homolog of the tumor suppressor p53. It is identified in basal cells in the epithelial layers of a variety of tissues, including epidermis, cervix, urothelium, breast and prostate. p63 was detected in nuclei of the basal epithelium in normal prostate glands; however, it was not expressed in malignant tumors of the prostate. As a result, p63 has been reported as a useful marker for differentiating benign from malignant lesions in the prostate, particularly when used in combination with markers of high molecular weight cytokeratins and the prostate-specific marker AMACR (P504S). p63 has also been shown to be a sensitive marker for lung squamous cell carcinomas (SqCC), with a sensitivity of ~90%. Specificity for lung SqCC, vs. lung adenocarcinoma (LADC), is approximately 80%. In breast tissue, p63 has been identified in myoepithelial cells of normal ducts.

Applicazioni

IHC-P

Diluizioni consigliate

IHC-P: 1-2 µg/ml

Reattività

Human

Immunogeno

Recombinant fragment, around amino acids 600-680, of human p63 protein. The exact sequence is proprietary.

Specie ospite

Rabbit

Clonalità

Monoclonal

Clona ID

TP63/4379R

Isotipo

IgG

Coniugare

Unconjugated

Purificazione

Protein A chromatography.

Concentrazione

200 µg/ml

Peso molecolare

63 kDa

Forma del prodotto

Liquid

Formulazione

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Conservazione

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Note generali

This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-p63 Antibody [TP63/4379R] - BSA and Azide free (A278670).

Sinonimi

AIS, Amplified in squamous cell carcinoma, B(p51A), B(p51B), Chronic ulcerative stomatitis protein, CUSP, DN p63 alpha 1, DNp63, EEC3, id:ibd3516, Keratinocyte transcription factor, Keratinocyte transcription factor KET, KET, LMS, MGC115972, MGC192897, NBP, OFC8, OTTHUMP00000209732, OTTHUMP00000209733, OTTHUMP00000209734, OTTHUMP00000209735, OTTHUMP00000209737, OTTHUMP00000209738, OTTHUMP00000209739, OTTHUMP00000209740, OTTHUMP00000209741, OTTHUMP00000209742, OTTHUMP00000209743, OTTHUMP00000209744, p40, p51, P51/P63, p53-related protein p63, p53CP, P63_HUMAN, p73H, p73L, RHS, SHFM4, TAp63alpha, TP53CP, TP53L, TP63, TP73L, Transformation related protein 63, Transformation-related protein 63, Trp53rp1, Trp63, Tumor protein 63, Tumor protein p53-competing protein, Tumor protein p53-like, Tumor protein p63, Tumor protein p63 deltaN isoform delta, Tumor protein p73, Tumor protein p73-like

Controlli isotipo

Secondari adatti

Dichiarazione di non responsabilità

Questo prodotto è solo per uso di ricerca. Non è inteso per uso diagnostico o terapeutico.

Immagini (3)

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Figure 1: Immunohistochemistry - Anti-p63 Antibody [TP63/4379R] (A278082)

Immunohistochemical analysis of formalin-fixed, paraffin-embedded human prostate cancer tissue using Anti-p63 Antibody [TP63/4379R]. Inset: PBS instead of the primary antibody. Secondary antibody negative control.

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Figure 2: Immunohistochemistry - Anti-p63 Antibody [TP63/4379R] (A278082)

Immunohistochemical analysis of formalin-fixed, paraffin-embedded human prostate cancer tissue using Anti-p63 Antibody [TP63/4379R].

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Figure 3: Anti-p63 Antibody [TP63/4379R] (A278082)

Analysis of protein array containing more than 19,000 full-length human proteins using Anti-p63 Antibody [TP63/4379R]. Z-Score and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProt^TM array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If targets on HuProt^TM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-score. S-score therefore represents the relative target specificity of a MAb to its intended target; a MAb is considered to be specific to its intended target, if the MAb has an S-score of at least 2.5. For example, if a MAb binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that MAb to protein X is equal to 29.