Anti-p27 KIP 1 Anticorpo (A283417)

Anti-p27 KIP 1 Antibody

Rabbit polyclonal antibody to p27 KIP 1.

This antibody recognises cyclin-dependent kinase inhibitor p27 (p27), also known as cyclin-dependent kinase inhibitor 1B or p27Kip1. The protein is a cyclin-dependent kinase inhibitor (CKI) that belongs to the Cip/Kip protein family. As the name implies, CKIs play a role in the regulation of cyclin-dependent kinases (CDKs) and cyclin-CDK complexes. Aberrant p27Kip1. levels have been reported in breast and colorectal cancers (Sgambato et al. 1997, Ogino et al. 2007).

WB

WB: 1:200

Human, Mouse, Rat

A peptide corresponding to the C-terminus of human p27/Kip1.

Rabbit

Polyclonal

IgG

Unconjugated

Affinity chromatography.

Approximately 27 kDa when run under reducing conditions

Liquid

Supplied in Phosphate Buffered Saline with 0.2% Gelatin and 0.1% Sodium Azide.

Store undiluted at 4°C. Do not freeze! Should this product contain a precipitate we recommend microcentrifugation before use.

Rabbit anti p27/Kip1 antibody recognizes cyclin-dependent kinase inhibitor p27 (p27), also known as cyclin-dependent kinase inhibitor 1B or p27Kip1. The protein is a cyclin-dependent kinase inhibitor (CKI) that belongs to the Cip/Kip protein family (Cerqueira et al. 2014). As the name implies, CKIs play a role in the regulation of cyclin-dependent kinases (CDKs) and cyclin-CDK complexes (Cerqueira et al. 2014).Aberrant p27Kip1. levels have been reported in breast and colorectal cancers (Sgambato et al. 1997, Ogino et al. 2007).

AA408329, AI843786, Cdki1b, CDKN 1B, CDKN 4, CDKN1B, CDKN4, CDN1B_HUMAN, Cyclin Dependent Kinase Inhibitor 1B, Cyclin dependent kinase inhibitor p27, Cyclin-dependent kinase inhibitor 1B, Cyclin-dependent kinase inhibitor 1B (p27, Kip1), Cyclin-dependent kinase inhibitor p27, Cyclin-dependent kinase inhibitor p27 Kip1, KIP 1, KIP1, MEN1B, MEN4, OTTHUMP00000195098, OTTHUMP00000195099, p27, p27 Kip1, P27-like cyclin-dependent kinase inhibitor, p27Kip1