Anti-p21 Anticorpo [AC8] (A251273)

Anticorpo monoclonale [AC8] di topo contro p21 per ELISA, WB, IP e IF.

Alternative Formats and ConjugatesAlternative Formats

Spese di spedizione
Tempi di consegna
4-6 Giorni lavorativi
Telefono
+1 (314) 370-6046
Lun - Ven, 8:00 - 16:00 AST
E-mail
orders@antibodies.com
Nome
Anti-p21 Antibody [AC8] - BSA and Azide free
Descrizione
Mouse monoclonal [AC8] antibody to p21.
Specificità
This antibody recognizes a 21kDa protein, identified as the p21WAF1 tumor suppressor protein. This antibody is highly specific to p21 and shows no cross-reaction with other closely related mitotic inhibitors. p21WAF1 is a specific inhibitor of cdks and a tumor suppressor involved in the pathogenesis of a variety of malignancies. The expression of this gene acts as an inhibitor of the cell cycle during G1 phase and is tightly controlled by the tumor suppressor protein p53. Its expression is induced by the wild type, but not mutant, p53 suppressor protein. Normal cells generally display a rather intense nuclear p21 expression. Loss of p21 expression has been reported in many carcinomas (gastric carcinoma, non-small cell lung carcinoma, thyroid carcinoma).
Applicazioni
ELISA, WB, IP, IF
Diluizioni consigliate
ELISA: 1-5 µg/ml, WB: 1-2 µg/ml, IP: 1-2 µg / 500 µg protein, IF: 1-2 µg/ml
Reattività
Human
Reattività incrociata
This antibody does not cross react with Mouse or Rat.
Immunogeno
Recombinant full-length human CDKN1A protein.
Specie ospite
Mouse
Clonalità
Monoclonal
Clona ID
AC8
Isotipo
IgG1
Catene leggere
kappa
Coniugare

Unconjugated

Purificazione
Protein A/G chromatography.
Concentrazione
1 mg/ml
Peso molecolare
21 kDa
Forma del prodotto
Liquid
Formulazione
Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.
Conservazione
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Note generali
This monoclonal antibody is also available in a different formulation with BSA and Sodium Azide - Anti-p21 Antibody [AC8] (A248090).
Sinonimi
CAP20, CDK-interacting protein 1, CDKI, CDKN1, Cdkn1a, CDN1A_HUMAN, CIP1, Cyclin Dependent Kinase Inhibitor 1A, Cyclin-dependent kinase inhibitor 1, Cyclin-dependent kinase inhibitor 1A (P21), Cyclin-dependent kinase inhibitor 1A (p21, Cip1), DNA Synthesis Inhibitor, MDA-6, MDA6, Melanoma differentiation-associated protein, Melanoma differentiation-associated protein 6, P21 protein, p21CIP1, p21Cip1/Waf1, p21WAF, PIC1, SDI1, SLC12A9, WAF1, Wild type p53 activated fragment 1, Wild type p53 activated fragment 1 (WAF1), Wildtype p53-activated fragment 1
Dichiarazione di non responsabilità
Questo prodotto è solo per uso di ricerca. Non è inteso per uso diagnostico o terapeutico.

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