Ricombinante Anti-Olig2 Anticorpo [OLIG2/7366R] (A315427)

Anti-Olig2 Antibody [OLIG2/7366R]

Recombinant rabbit monoclonal [OLIG2/7366R] antibody to Olig2.

Olig2, a basic helix-loop-helix transcription factor, is involved in oligo-dendroglial specification. Olig2 expression has been reported in most glial tumors, such as oligodendrogliomas and astrocytomas. Although more than half of glioblastomas are positive for Olig2, expression is very weak in terms of both percentage of labeled cells and intensity. No Olig2 expression has been found in the non-glial tumors including neuroepithelial tumors, ependymomas, sub-ependymomas, medulloblastomas, and non-neuroepithelial tumors, such as CNS lymphomas, meningiomas, schwannomas, atypical teratoid/rhabdoid tumor, and haemangioblastomas. Compared to the strong staining seen in glioma samples, a weak expression is observed in non-tumoral brain tissue.

IHC-P

THP-1 cells. Human brain or astrocytoma.

IHC: 1-2 µg/ml

Human

Recombinant fragment (around Amino Acids 200-300) of human OLIG2 protein. The exact sequence is proprietary.

Rabbit

Monoclonal

OLIG2/7366R

IgG

Unconjugated

Protein A/G chromatography.

200 µg/ml

32 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Basic domain helix loop helix protein class B 1, Basic helix loop helix protein class B 1, BHLHB, bHLHB1, bHLHe19, Class B basic helix loop helix protein 1, Class B basic helix-loop-helix protein 1, class E basic helix loop helix protein 19, Class E basic helix-loop-helix protein 19, Human protein kinase C binding protein RACK17, OLIG2_HUMAN, Oligo2, Oligodendrocyte lineage transcription factor 2, Oligodendrocyte specific bHLH transcription factor 2, Oligodendrocyte transcription factor 2, OTTHUMP00000067569, OTTHUMP00000067570, PRKCBP2, Protein kinase C binding protein 2, Protein kinase C binding protein RACK17, Protein kinase C-binding protein 2, Protein kinase C-binding protein RACK17, RACK17