Anti-NME2 Anticorpo [NME2/6437] (A315399)

$765

Anticorpo monoclonale [NME2/6437] di topo contro NME2 per WB e IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Spese di spedizione
Tempi di consegna
4-6 Giorni lavorativi
Telefono
+1 (314) 370-6046
Lun - Ven, 8:00 - 16:00 AST
E-mail
orders@antibodies.com
Nome
Anti-NME2 Antibody [NME2/6437]
Descrizione
Mouse monoclonal [NME2/6437] antibody to NME2.
Specificità
The nm23 gene, a potential suppressor of metastasis, was originally identified by differential hybridization between two murine melanoma sub-lines, one with a high and the second with a low metastatic capacity. Highly metastatic sub-lines exhibit much lower levels of nm23 than less metastatic cells. Based on sequence analysis, nm23 appears highly related to nucleotide diphosphate kinases (NDP). In humans, NDP kinases A and B are identical to two isotypes of human nm23 homologs, namely nm23-H1 and H2, respectively. nm23-H2 is identical in sequence to PuF, a transcription factor that binds to nuclease hypersensitive elements at positions 142 to 115 of the human c-Myc promotor.
Applicazioni
WB, IHC-P
Controllo positivo
MCF-7, HEK293, HeLa or Jurkat cells. Ubiquitously expressed in all tissues.
Diluizioni consigliate
WB: 1-2 µg/ml, IHC: 1-2 µg/ml
Reattività
Human
Immunogeno
Recombinant full-length human NME2 protein.
Specie ospite
Mouse
Clonalità
Monoclonal
Clona ID
NME2/6437
Isotipo
IgG1
Catene leggere
kappa
Coniugare

Unconjugated

Purificazione
Protein A/G chromatography.
Concentrazione
200 µg/ml
Peso molecolare
17 kDa
Forma del prodotto
Liquid
Formulazione
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Conservazione
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Sinonimi
C myc purine binding transcription factor PUF, C myc transcription factor, C-myc purine-binding transcription factor PUF, epididymis secretory sperm binding protein Li 155an, HEL-S-155an, Histidine protein kinase NDKB, MGC111212, MGC2212, NDK B, NDKB, NDKB_HUMAN, NDP kinase B, NDPK B, NDPKB, NM23 H2, nm23-H2, NM23B, NME/NM23 nucleoside diphosphate kinase 2, Non metastatic cells 2, protein (NM23B) expressed in, non-metastatic cells 2, protein (NM23) expressed in, Nucleoside diphosphate kinase B, Nucleotide diphosphate kinase B, PUF
Dichiarazione di non responsabilità
Questo prodotto è solo per uso di ricerca. Non è inteso per uso diagnostico o terapeutico.

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