Anti-Neuron Specific Enolase Anticorpo [SPM347] (A251617)

Anti-Neuron Specific Enolase Antibody [SPM347] - BSA and Azide free

Mouse monoclonal [SPM347] antibody to Neuron Specific Enolase.

This antibody recognizes a protein of about 50kDa, which is identified as gamma-enolase. Three isoenzymes of enolases are identified, alpha, beta and gamma. Alpha-isoform is expressed in most tissues, whereas beta-form is expressed predominantly in muscle tissue whereas gamma-enolase is found only in nervous tissue. These isoforms exist as both homodimers and heterodimers, and they play a role in converting phosphoglyceric acid to phosphenolpyruvic acid in the glycolytic pathway. NSE-gamma is a useful marker to identify peripheral nerves and tumors of neuro-endocrine origins, such as pheochromocytomas.It it be usually employed in combination with other markers such as Synaptophysin,Chromogranin A, and Neurofilament.

Flow Cytometry, IF, WB, IHC-P

Flow Cytometry: 1-2 µg/million cells, IF: 1-2 µg/ml, WB: 1-2 µg/ml, IHC-P: 1-2 µg/ml

Human

Synthetic peptide, within amino acids 416-433, of human NSE gamma. The exact sequence is proprietary.

Mouse

Monoclonal

SPM347

IgG2b

kappa

Protein A/G chromatography.

1 mg/ml

~50 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

This monoclonal antibody is also available in a different formulation with BSA and Sodium Azide - Anti-Neuron Specific Enolase Antibody [SPM347] (A248435).

2 phospho D glycerate hydrolyase, 2-phospho-D-glycerate hydro-lyase, Eno 2, ENO2, ENOG, ENOG_HUMAN, Enolase 2, Enolase 2 (gamma, neuronal), Enolase 2 gamma neuronal, Enolase2, Epididymis secretory protein Li 279, Gamma enolase, Gamma-enolase, HEL S 279, Neural enolase, Neuron specific gamma enolase, Neuron-specific enolase, neuronal enriched enolase, Neurone specific enolase, NSE