Anti-Neurofilament Heavy Polypeptide Anticorpo [NE14] (A252671)

Anticorpo monoclonale [NE14] di topo contro Neurofilament Heavy Polypeptide per WB, Flow Cytometry e IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Spese di spedizione
Tempi di consegna
4-6 Giorni lavorativi
Telefono
+1 (314) 370-6046
Lun - Ven, 8:00 - 16:00 AST
E-mail
orders@antibodies.com
Nome
Anti-Neurofilament Heavy Polypeptide Antibody [NE14] - BSA and Azide free
Descrizione
Mouse monoclonal [NE14] antibody to Neurofilament Heavy Polypeptide.
Specificità
This antibody reacts with a 200kDa protein, identified as heavy sub-unit of neurofilaments (NF-H). It reacts specifically with the phosphorylated KSP/KEP segment at the C-terminus of the heavy subunit (NF-H) of neurofilaments. After dephosphorylation of neurofilaments with alkaline phosphatase, this Ab no longer binds. Neurofilaments make up the main structural elements of axons and dendrites and are found in neurons, peripheral nerves, and sympathetic ganglion cells. Neurofilaments consist of three major subunits with molecular weights of 68kDa (NF-L), 160kDa (NF-M) and 200kDa (NF-H). Anti-neurofilament stains a number of neural, neuroendocrine, and endocrine tumors. Neuromas, ganglioneuromas, gangliogliomas, ganglioneuroblastomas, and neuroblastomas stain positively for anti-neurofilament. Neurofilaments are also present in paragangliomas as well as adrenal and extra-adrenal pheochromocytomas. Carcinoids, neuroendocrine carcinomas of the skin, and oat cell carcinomas of the lung also express neurofilament.
Applicazioni
WB, Flow Cytometry, IHC-P
Diluizioni consigliate
WB: 1-2 µg/ml, Flow Cytometry: 1-2 µg/million cells, IHC-P: 0.25-0.5 µg/ml
Reattività
Human, Mouse, Rat, Guinea Pig, Gerbil, Feline, Porcine, Rabbit, Bovine, Chicken
Immunogeno
Crude neurofilament preparation from porcine spinal cord.
Specie ospite
Mouse
Clonalità
Monoclonal
Clona ID
NE14
Isotipo
IgG1
Catene leggere
kappa
Coniugare

Unconjugated

Purificazione
Protein A/G chromatography.
Concentrazione
1 mg/ml
Peso molecolare
200 kDa
Forma del prodotto
Liquid
Formulazione
Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.
Conservazione
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Note generali
This monoclonal antibody is also available in a different formulation with BSA and Sodium Azide - Anti-Neurofilament Heavy Polypeptide Antibody [NE14] (A249491).
Sinonimi
200 kDa neurofilament protein, CMT2CC, Nefh, Neurofilament heavy polypeptide 200kDa, Neurofilament triplet H protein, NF H, NF-H, NFH, NFH_HUMAN
Dichiarazione di non responsabilità
Questo prodotto è solo per uso di ricerca. Non è inteso per uso diagnostico o terapeutico.

Prodotti alternativi a Anti-Neurofilament Heavy Polypeptide Anticorpo [NE14] (A252671)

Inizio pagina