Anti-NACC1 Anticorpo [PCRP-NACC1-1A8] (A248213)

Anticorpo monoclonale [PCRP-NACC1-1A8] di topo contro NACC1 per Flow Cytometry.

Alternative Formats and ConjugatesAlternative Formats

Spese di spedizione
Tempi di consegna
4-6 Giorni lavorativi
Telefono
+1 (314) 370-6046
Lun - Ven, 8:00 - 16:00 AST
E-mail
orders@antibodies.com
Nome
Anti-NACC1 Antibody [PCRP-NACC1-1A8]
Descrizione
Mouse monoclonal [PCRP-NACC1-1A8] antibody to NACC1.
Specificità
The BTB (broad-complex, tramtrack and bric a brac) domain, also known as the POZ (poxvirus and zinc finger) domain, is an N-terminal homodimerization domain that contains multiple copies of kelch repeats and/or C2H2-type zinc fingers. Proteins that contain BTB domains are thought to be involved in transcriptional regulation via control of chromatin structure and function. BTBD14B (BTB/POZ domain-containing protein 14B), also known as NACC1 (nucleus accumbens associated 1), BEND8 or NAC1, is a 527 amino acid protein that localizes to both the nucleus and the cytoplasm and contains one BTB (POZ) domain. Existing as a homo-oligomer that interacts with HDAC3 and HDAC4, BTBD14B functions as a transcriptional repressor that influences the transcriptional activity of CRIF1 and is required for proteasome recruitment to the nucleus and cytoplasm in dendritic spines. BTBD14B is overexpressed in multiple carcinomas, suggesting a role in tumor development and metastasis.
Applicazioni
Flow Cytometry
Diluizioni consigliate
Flow Cytometry: 1-2 µg/million cells
Reattività
Human
Immunogeno
Recombinant full-length human NACC1 protein.
Specie ospite
Mouse
Clonalità
Monoclonal
Clona ID
PCRP-NACC1-1A8
Isotipo
IgG2a
Coniugare

Unconjugated

Purificazione
Protein A/G chromatography.
Concentrazione
200 µg/ml
Peso molecolare
57 kDa
Forma del prodotto
Liquid
Formulazione
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Conservazione
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Note generali
This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-NACC1 Antibody [PCRP-NACC1-1A8] - BSA and Azide free (A251396).
Sinonimi
BEND8, BTB Domain Containing 14B, BTB/POZ domain-containing protein 14B, btbd14b, FLJ37383, NAC-1, Nac1, NACC1_HUMAN, Nucleus accumbens-associated protein 1
Dichiarazione di non responsabilità
Questo prodotto è solo per uso di ricerca. Non è inteso per uso diagnostico o terapeutico.

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