This antibody recognises human myosin regulatory light chain (MRLC), also known as MYL9 and LC20.Myosin is a hexamer composed of two high molecular weight heavy chains and four light chain subunits, which include two alkali light chains and two MRLCs. MRLC functions to stabilize the myosin heavy chain, and may also modulate the availability of cross bridges to bind to actin. Phosphorylation of the MRLC by myosin light chain kinase (MLCK) is necessary for smooth muscle contraction via activating myosin ATPase.

Applicazioni

WB, IHC-P, ELISA

Diluizioni consigliate

ELISA: 1:5,000 - 1:20,000, IHC-P: 2.5 µg/ml, WB: 1:500 - 1:2,000

Reattività

Human, Birds, Mammals, Mouse, Rat

Immunogeno

Synthetic peptide corresponding to amino acids 12-27 of human Myosin Regulatory Light Chain.

Sequenza

KKRPQRATSNVFAMFD

Specie ospite

Rabbit

Clonalità

Polyclonal

Isotipo

IgG

Coniugare

Unconjugated

Concentrazione

500 µg/ml

Forma del prodotto

Liquid

Formulazione

Supplied in Phosphate Buffered Saline with <0.1% Sodium Azide.

Conservazione

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Note generali

Rabbit anti Human myosin regulatory light chain antibody recognizes human myosin regulatory light chain (MRLC), also known as MYL9 and LC20. Myosin is a hexamer composed of two high molecular weight heavy chains and four light chain subunits, which include two alkali light chains and two MRLCs. MRLC functions to stabilize the myosin heavy chain, and may also modulate the availability of cross bridges to bind to actin. Phosphorylation of the MRLC by myosin light chain kinase (MLCK) is necessary for smooth muscle contraction via activating myosin ATPase.

Sinonimi

20 kDa myosin light chain, Human 20kDa myosin light chain (MLC2) mRNA complete cds, LC20, MGC3505, MLC 2, MLC-2C, MLC2, MLY 9, MRLC1, MYL9_HUMAN, Myosin light chain 9 regulatory, Myosin light polypeptide 9 regulatory, myosin regulatory light chain 1, Myosin regulatory light chain 2, Myosin regulatory light chain 2 smooth muscle isoform, Myosin regulatory light chain 9, Myosin regulatory light chain MRLC1, Myosin regulatory light polypeptide 9, Myosin RLC, Myosin vascular smooth muscle light chain 2, MYRL2, OTTHUMP00000030857, smooth muscle isoform

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Secondari adatti

Dichiarazione di non responsabilità

Questo prodotto è solo per uso di ricerca. Non è inteso per uso diagnostico o terapeutico.