Anti-MUC16 Anticorpo [OCA125/1900] (A250625)

Name: Anti-MUC16 Antibody [OCA125/1900]
Brand: Antibodies.com
SKU: A250625
Price: 525.0 USD
Availability: InStock

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$525

Anticorpo monoclonale [OCA125/1900] di topo contro MUC16 per IHC-P.

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Alternative Formats and ConjugatesAlternative Formats

Carrier Free and Preservative Free

Consegna

Spese di spedizione

$40

Tempi di consegna

4-6 Giorni lavorativi

Contattaci

Telefono

+1 (314) 370-6046

E-mail

orders@antibodies.com

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Descrizione Prodotto

Nome

Anti-MUC16 Antibody [OCA125/1900]

Descrizione

Mouse monoclonal [OCA125/1900] antibody to MUC16.

Specificità

The mucins are a family of highly glycosylated, secreted proteins with a basic structure consisting of a variable number of tandem repeats (VNTRs). Membrane-associated and secretory Mucins are high molecular weight glycoproteins of the glycocalyx (polysaccharide biofilm) that protects mucosal epithelium from particulate matter and microorganisms. Epithelial Mucins are large, secreted and cell surface glycoproteins crucial for adhesion modulation, signaling and epithelial cell protection. The number of repeats is highly polymorphic and varies among different alleles. The Mucin family consists of Mucins 1-4, Mucin 5 (AC and B), Mucins 6-8, Mucins 11-13 and Mucins 15-17. The Mucin 16 protein (also commonly referred to as CA125), encoded for by the gene MUC16, is a very high molecular weight tumor antigen consisting of three domains: a carboxy terminal domain, an extracellular domain and an amino terminal domain. Mucin 16, an ovarian cancer-associated antigen, is used as a marker to monitor the progress of epithelial ovarian cancer. It is a hydrophilic membrane-associated protein that may be involved in vitamin A functions.

Applicazioni

IHC-P

Diluizioni consigliate

IHC-P: 1-2 µg/ml

Reattività

Human

Immunogeno

Native full-length human MUC16 protein, purified from human ovarian carcinoma.

Specie ospite

Mouse

Clonalità

Monoclonal

Clona ID

OCA125/1900

Isotipo

IgG1

Catene leggere

kappa

Coniugare

Unconjugated

Purificazione

Protein A/G chromatography.

Concentrazione

200 µg/ml

Peso molecolare

>2,000 kDa

Forma del prodotto

Liquid

Formulazione

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Conservazione

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Note generali

This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-MUC16 Antibody [OCA125/1900] - BSA and Azide free (A253805).

Sinonimi

CA 125, CA-125, CA125, CA125 ovarian cancer antigen, Cancer antigen 125, FLJ14303, MUC 16, MUC-16, MUC16_HUMAN, Mucin 16, Mucin 16 cell surface associated, Mucin-16, Mucin16, Ovarian cancer related tumor marker CA125, Ovarian cancer-related tumor marker CA125, Ovarian carcinoma antigen CA125

Controlli isotipo

Secondari adatti

Dichiarazione di non responsabilità

Questo prodotto è solo per uso di ricerca. Non è inteso per uso diagnostico o terapeutico.

Immagini (2)

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Figure 1: Immunohistochemistry - Anti-MUC16 Antibody [OCA125/1900] (A250625)

Immunohistochemical analysis of formalin-fixed, paraffin-embedded human ovarian carcinoma using Anti-MUC16 Antibody [OCA125/1900].

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Figure 2: SDS-PAGE - Anti-MUC16 Antibody [OCA125/1900] (A250625)

SDS-PAGE analysis of Anti-MUC16 Antibody [OCA125/1900] under non-reduced and reduced conditions; showing intact IgG and intact heavy and light chains, respectively. SDS-PAGE analysis confirms the integrity and purity of the antibody.