Anti-MMP2 Anticorpo [4D3] (A316711)

$765

Anticorpo monoclonale [4D3] di topo contro MMP2 per IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Spese di spedizione
Tempi di consegna
4-6 Giorni lavorativi
Telefono
+1 (314) 370-6046
Lun - Ven, 8:00 - 16:00 AST
E-mail
orders@antibodies.com
Nome
Anti-MMP2 Antibody [4D3] - BSA and Azide free
Descrizione
Mouse monoclonal [4D3] antibody to MMP2.
Specificità
It recognizes a protein of 72kDa, which is identified as MMP2. The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, Fibronectin, Laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB). MMP catalysis requires both calcium and zinc. MMP-2 (also designated type IV collagenase) cleaves collagen types IV,V, VII and X and gelatin type I. Activation of MMP-2 secretion requires the Ras signaling pathway.
Applicazioni
IHC-P
Controllo positivo
U-138 MG or U-87 MG cells. Human placenta or colon carcinoma.
Diluizioni consigliate
IHC: 1-2 µg/ml
Reattività
Human
Immunogeno
Recombinant human MMP2 protein fragment (aa557-569).
Specie ospite
Mouse
Clonalità
Monoclonal
Clona ID
4D3
Isotipo
IgG1
Coniugare

Unconjugated

Purificazione
Protein A/G chromatography.
Concentrazione
1 mg/ml
Peso molecolare
72 kDa (Pro) / 63 kDa (cleaved)
Forma del prodotto
Liquid
Formulazione
Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.
Conservazione
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Sinonimi
72 kDa gelatinase, 72 kDa type IV collagenase, 72kD type IV collagenase, CLG 4, CLG 4A , CLG4, CLG4A, Collagenase Type 4 alpha, Collagenase type IV A, EC 3.4.24.24, Gelatinase A, Gelatinase alpha , Gelatinase neutrophil , Matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase), Matrix metallopeptidase 2 gelatinase A 72kDa gelatinase 72kDa type IV collagenase, Matrix metalloproteinase 2, Matrix metalloproteinase 2 (gelatinase A, 72kD gelatinase, 72kD type IV collagenase), Matrix metalloproteinase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase), Matrix metalloproteinase II, Matrix metalloproteinase-2, MMP 2, MMP II, MMP-2, MMP2_HUMAN, MONA, Neutrophil gelatinase, PEX, TBE 1, TBE-1
Dichiarazione di non responsabilità
Questo prodotto è solo per uso di ricerca. Non è inteso per uso diagnostico o terapeutico.

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