Anti-MED7 Anticorpo [PCRP-MED7-1B8] (A278439)

Anticorpo monoclonale [PCRP-MED7-1B8] di topo contro MED7 per ELISA, Flow Cytometry, IF e IP.

Alternative Formats and ConjugatesAlternative Formats

Spese di spedizione
Tempi di consegna
4-6 Giorni lavorativi
Telefono
+1 (314) 370-6046
Lun - Ven, 8:00 - 16:00 AST
E-mail
orders@antibodies.com
Nome
Anti-MED7 Antibody [PCRP-MED7-1B8] - BSA and Azide free
Descrizione
Mouse monoclonal [PCRP-MED7-1B8] antibody to MED7.
Specificità
MED7, also known as HKQ, QK, QK3 or quaking, is a 341 amino acid protein that localizes to both the cytoplasm and the nucleus and contains one KH domain. Expressed in the frontal cortex of the brain, MED7 functions as an RNA-binding protein that plays an important role in myelinization and specifically binds to the RNA core sequence 5'-NACUAAY-N(1,20)-UAAY-3'. Additionally, MED7 regulates pre-mRNA splicing, and mRNA export and is involved in protecting and promoting the stability of select mRNAs. MED7 may be methylated by PRMT1 and may also be phosphorylated at its C-terminus, an event that decreases MED7 mRNA-binding affinity. Defects or deletions in the gene encoding MED7 are associated with astrocytic tumors and may be involved in the pathogenesis of schizophrenia. Multiple isoforms of MED7 exist due to alternative splicing events.
Applicazioni
ELISA, Flow Cytometry, IF, IP
Diluizioni consigliate
Flow Cytometry: 1-2 µg/million cells, IF: 1-2 µg/ml, IP: 1-2µg / 100-500µg proteins
Reattività
Human
Immunogeno
Recombinant full-length human MED7 protein.
Specie ospite
Mouse
Clonalità
Monoclonal
Clona ID
PCRP-MED7-1B8
Isotipo
IgG2b
Coniugare

Unconjugated

Purificazione
Protein A/G chromatography.
Concentrazione
1 mg/ml
Peso molecolare
27.2 kDa
Forma del prodotto
Liquid
Formulazione
Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.
Conservazione
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Note generali
This monoclonal antibody is also available in a different formulation with BSA and Sodium Azide - Anti-MED7 Antibody [PCRP-MED7-1B8] (A277851).
Sinonimi
Activator recruited cofactor 34 kDa component, Activator-recruited cofactor 34 kDa component, ARC34, Cofactor required for Sp1 transcriptional activation subunit 9, Cofactor required for Sp1 transcriptional activation, subunit 9 (33kD), Cofactor required for Sp1 transcriptional activation, subunit 9, 33kDa, CRSP complex subunit 9, CRSP33, CRSP9, hMED7, MED7_HUMAN, Mediator complex subunit 7, Mediator of RNA polymerase II transcription subunit 7, MGC12284, RNA polymerase transcriptional regulation mediator subunit 7 homolog, Transcriptional coactivator CRSP33
Dichiarazione di non responsabilità
Questo prodotto è solo per uso di ricerca. Non è inteso per uso diagnostico o terapeutico.

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