Anti-MCP1 Anticorpo [AA03-4H10] (Biotin) (A279615)

$420

Anticorpo monoclonale [AA03-4H10] di topo contro MCP1 (Biotin) per ELISA.

Spese di spedizione
Tempi di consegna
4-6 Giorni lavorativi
Telefono
+1 (314) 370-6046
Lun - Ven, 8:00 - 16:00 AST
E-mail
orders@antibodies.com
Nome
Anti-MCP1 Antibody [AA03-4H10] (Biotin)
Descrizione
Mouse monoclonal [AA03-4H10] antibody to MCP1 (Biotin).
Specificità
This antibody recognises C-C motif chemokine 2, also known as MCP1, HC11, and MCAF. CCL2 is a constitutively expressed chemokine, which is upregulated during the inflammatory response and promotes recruitment of immune cells to specific sites. Many cell types can produce CCL2, including endothelial, epithelial, myeloid, smooth muscle cells and fibroblasts, and CCL2 is able to recruit monocytes, basophils, T lymphocytes and NK cells. CCL2 promotes cancer development and metastasis through binding to the cognate receptor CCR2, and CCL2-CCR2 signaling has multiple tumorigenic roles. The tumor microenvironment itself produces CCL2, which facilitates the accumulation of tumor associated macrophages (TAMs), which have immune suppressive and tumor promoting functions. The biotinylated Mouse anti Human CCL2 antibody, clone AA03-4H10 (MCA6219B) can be used as a detection antibody in a sandwich ELISA with the purified Mouse anti Human CCL2 antibody, clone AA07-3B8 (MCA6218GA) as the capture antibody.
Applicazioni
ELISA
Diluizioni consigliate
ELISA: 1 µg/ml
Reattività
Human
Immunogeno
E. coli derived recombinant human CCL2 (Gln24-Thr99).
Specie ospite
Mouse
Clonalità
Monoclonal
Clona ID
AA03-4H10
Isotipo
IgG1
Coniugare

Biotin

Purificazione
Protein G affinity chromatography of tissue culture supernatant.
Concentrazione
100 µg/ml
Forma del prodotto
Liquid
Formulazione
Supplied in Phosphate Buffered Saline with 1% BSA and 0.09% Sodium Azide.
Conservazione
Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended. This product is photosensitive and should be protected from light.
Note generali
Mouse anti Human CCL2 antibody, clone AA03-4H10, recognizes C-C motif chemokine 2, also known as MCP1, HC11, and MCAF. CCL2 is a constitutively expressed chemokine, which is upregulated during the inflammatory response and promotes recruitment of immune cells to specific sites. Many cell types can produce CCL2, including endothelial, epithelial, myeloid, smooth muscle cells and fibroblasts, and CCL2 is able to recruit monocytes, basophils, T lymphocytes and NK cells (Lim et al. 2016). CCL2 promotes cancer development and metastasis through binding to the cognate receptor CCR2, and CCL2-CCR2 signaling has multiple tumorigenic roles. The tumor microenvironment itself produces CCL2, which facilitates the accumulation of tumor associated macrophages (TAMs), which have immune suppressive and tumor promoting functions (Yoshimura et al. 2018). The biotinylated Mouse anti Human CCL2 antibody, clone AA03-4H10 (MCA6219B) can be used as a detection antibody in a sandwich ELISA with the purified Mouse anti Human CCL2 antibody, clone AA07-3B8 (MCA6218GA) as the capture antibody.
Sinonimi
C-C motif chemokine 2, CCL2, CCL2_HUMAN, Chemokine (C C motif) ligand 2, GDCF 2, GDCF-2, GDCF2, HC11, HSMCR30, JE, MCAF, MCP 1, MCP-1, MGC9434, Monocyte chemoattractant protein 1, Monocyte chemotactic and activating factor, Monocyte chemotactic protein 1, Monocyte secretory protein JE, SCYA2, Small inducible cytokine A2, Small inducible cytokine A2 (monocyte chemotactic protein 1, homologous to mouse Sig je), Small inducible cytokine subfamily A (Cys Cys), member 2, Small-inducible cytokine A2, SMC CF, SMC-CF, SMCCF
Dichiarazione di non responsabilità
Questo prodotto è solo per uso di ricerca. Non è inteso per uso diagnostico o terapeutico.

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