Anti-MCM6 Anticorpo [MCM6/2999] (A249298)

Anticorpo monoclonale [MCM6/2999] di topo contro MCM6 per IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Spese di spedizione
Tempi di consegna
4-6 Giorni lavorativi
Telefono
+1 (314) 370-6046
Lun - Ven, 8:00 - 16:00 AST
E-mail
orders@antibodies.com
Nome
Anti-MCM6 Antibody [MCM6/2999]
Descrizione
Mouse monoclonal [MCM6/2999] antibody to MCM6.
Specificità
The mini-chromosome maintenance (MCM) family of proteins, including MCM2, MCM3, MCM6 (Cdc21), MCM5 (Cdc46), MCM6 (Mis5) and MCM7 (Cdc47), are regulators of DNA replication that act to ensure replication occurs only once in the cell cycle. Expression of MCM proteins increases during cell growth, peaking at G1/S phase. The MCM proteins each contain an ATP-binding motif, which is predicted to mediate ATP-dependent opening of double-stranded DNA. MCM proteins are regulated by E2F transcription factors, which induce MCM expression, and by protein kinases, which interact with MCM proteins to maintain the post-replicative state of the cell. MCM2/MCM6 complexes function as substrates for Cdc2/cyclin B in vitro.
Applicazioni
IHC-P
Diluizioni consigliate
IHC-P: 1-2 µg/ml
Reattività
Human
Immunogeno
Recombinant fragment, around amino acids 228-368, of human MCM6 protein. The exact sequence is proprietary.
Specie ospite
Mouse
Clonalità
Monoclonal
Clona ID
MCM6/2999
Isotipo
IgG2b
Catene leggere
kappa
Coniugare

Unconjugated

Purificazione
Protein A/G chromatography.
Concentrazione
200 µg/ml
Peso molecolare
105 kDa
Forma del prodotto
Liquid
Formulazione
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Conservazione
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Note generali
This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-MCM6 Antibody [MCM6/2999] - BSA and Azide free (A252478).
Sinonimi
DNA replication licensing factor MCM6, MCG40308, MCM6 minichromosome maintenance deficient 6, MCM6 minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe), MCM6_HUMAN, Minichromosome maintenance complex component 6, Minichromosome maintenance deficient (mis5 S. pombe) 6, Minichromosome maintenance deficient 6 homolog, Minichromosome maintenance protein 6, Mis5, MIS5 homolog, p105MCM
Dichiarazione di non responsabilità
Questo prodotto è solo per uso di ricerca. Non è inteso per uso diagnostico o terapeutico.

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