Ricombinante Anti-LI Cadherin Anticorpo [CDH17/8513R] (A315250)

Anti-LI Cadherin Antibody [CDH17/8513R]

Recombinant rabbit monoclonal [CDH17/8513R] antibody to LI Cadherin.

It recognizes a protein of 120kDa, which is identified as Cadherin 17 (also known as LI Cadherin). The cadherins are a family of Calcium-dependent adhesion molecules that function to mediate cell-cell binding critical to the maintenance of tissue structure and morphogenesis. Cadherins each contain a large extracellular domain at the amino terminus, which is characterized by a series of five homologous repeats, the most distal of which is thought to be responsible for binding specificity. The relatively short carboxy terminal, intracellular domain interacts with a variety of cytoplasmic proteins, including beta-catenin, to regulate cadherin function. LI-cadherin (for liver-intestine-cadherin) expression is restricted to liver and intestine tissues and is specifically localized to the basolateral domain of hepatocytes and enterocytes.

IHC-P

HepG2 or HT29 cells. Stomach, Small Intestine, Colon or liver

IHC: 1-2 µg/ml

Human

Recombinant fragment (around Amino Acids 242-418) of human Cadherin 17 protein (CDH17). The exact sequence is proprietary.

Rabbit

Monoclonal

CDH17/8513R

IgG

Unconjugated

Protein A chromatography.

200 µg/ml

120 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

BILL-cadherin, CAD17_HUMAN, Cadherin 16, Cadherin 16, formerly, Cadherin 17, cadherin 17, LI cadherin (liver-intestine), cadherin, liver-intestine, Cadherin-17, CDH16, CDH16, formerly, Cdh17, FLJ26931, Formerly Cadherin 16, Formerly CDH16, HPT 1, HPT-1 cadherin, human intestinal peptide-associated transporter HPT-1, human peptide transporter 1, Intestinal peptide-associated transporter HPT 1, Intestinal peptide-associated transporter HPT-1, LI-cadherin, Liver Cadherin, liver intestine cadherin, Liver-intestine cadherin