Anti-Insulin Anticorpo [SPM139] (A252217)

Anti-Insulin Antibody [SPM139] - BSA and Azide free

Mouse monoclonal [SPM139] antibody to Insulin.

This antibody recognizes a polypeptide which is identified as insulin, a 51-amino acid polypeptide composed of A and B chains connected through the C-peptide. Proinsulin, which has very little biological activity, is cleaved by proteases within its cell of origin into the insulin molecule and the C-terminal basic residue. Insulin enhances membrane transport of glucose, amino acids, and certain ions. It also promotes glycogen storage, formation of triglycerides, and synthesis of proteins and nucleic acids. Deficiency of insulin results in diabetes mellitus. The main storage site for insulin is the pancreatic islets. Antibodies to insulin are important as beta-cell and insulinoma marker.

Flow Cytometry, IF, IHC-P

Flow Cytometry: 1-2 µg/million cells, IF: 1-2 µg/ml, IHC-P: 1-2 µg/ml

Huma, Bovine, Porcine

This antibody does not cross react with Mouse or Rat.

Purified full-length (1-84 amino acid) pig insulin, conjugated to KLH.

Mouse

Monoclonal

SPM139

IgG1

Unconjugated

Protein A/G chromatography.

1 mg/ml

6 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

This monoclonal antibody is also available in a different formulation with BSA and Sodium Azide - Anti-Insulin Antibody [SPM139] (A249037).

IDDM, IDDM1, IDDM2, ILPR, ins, Insulin A chain, Insulin B chain, INS_HUMAN, IRDN, MODY10, Preproinsulin, Proinsulin, Proinsulin precursor