This antibody recognises interleukin-9 (IL-9), also known as cytokine P40 and T cell growth factor P40. IL-9 is a member of the common gamma chain receptor cytokine family that is expressed by multiple cell types including T cell subsets, neutrophils, eosinophils, natural killer T cells and mast cells (Noelle & Nowak 2010, Chakraborty et al. 2019).IL-9 is a ligand of IL-9 receptor alpha (IL-9RA) and upon binding of IL-9 to its receptor the JAK, PI3K, STAT and MAPK signaling pathways can be activated. This can then result in the stimulation of expression of genes that play roles in transplant tolerance, allergies, autoimmunity and parasitic infection.

Applicazioni

WB, ELISA

Diluizioni consigliate

ELISA: 0.5 µg/ml - 2.0 µg/ml, WB: 0.1 µg/ml - 0.2 µg/ml

Reattività

Mouse

Immunogeno

E. coli derived recombinant mouse interleukin-9.

Specie ospite

Rabbit

Clonalità

Polyclonal

Isotipo

IgG

Coniugare

Unconjugated

Concentrazione

1 mg/ml after reconstitution.

Forma del prodotto

Lyophilized

Ricostituzione

Reconstitute with 0.1 ml of distilled water.

Formulazione

Supplied in Phosphate Buffered Saline.

Conservazione

Lyophilized: Store at -20°C. Reconstituted: Store undiluted at -20°C, avoid freeze / thaw cycles. Storage in frost free freezers is not recommended. Should this product contain a precipitate we recommend microcentrifugation before use.

Note generali

Rabbit anti Mouse interleukin-9 antibody, recognizes interleukin-9 (IL-9), also known as cytokine P40 and T cell growth factor P40. IL-9 is a member of the common gamma chain receptor cytokine family that is expressed by multiple cell types including T cell subsets, neutrophils, eosinophils, natural killer T cells and mast cells (Noelle & Nowak 2010, Chakraborty et al. 2019). IL-9 is a ligand of IL-9 receptor alpha (IL-9RA) and upon binding of IL-9 to its receptor the JAK, PI3K, STAT and MAPK signaling pathways can be activated (Chakraborty et al. 2019). This can then result in the stimulation of expression of genes that play roles in transplant tolerance, allergies, autoimmunity and parasitic infection (Noelle & Nowak 2010).

Sinonimi

Cytokine P40, Homolog of mouse T cell and mast cell growth factor 40 , HP40, IL 9, IL9, IL9_HUMAN, Interleukin 9 , Interleukin-9, Mast cell growth factor , MCGF, Megakaryoblast growth factor, P40, p40 cytokine , p40 T cell and mast cell growth factor, T cell growth factor 3, T cell growth factor p40 , T-cell growth factor P40, TCGF 3

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Dichiarazione di non responsabilità

Questo prodotto è solo per uso di ricerca. Non è inteso per uso diagnostico o terapeutico.