Anti-IL-32 Anticorpo [E03-4C9] (A280288)

Anti-IL-32 Antibody [E03-4C9]

Mouse monoclonal [E03-4C9] antibody to IL-32.

This antibody recognises interleukin-32 (IL-32), also known as NK4 and TAIF. IL-32 is a pro-inflammatory cytokine with roles in inflammation and immune regulation, and its expression is strongly regulated by pathogens and pro-inflammatory cytokines. IL-32 promotes inflammation by upregulating other inflammatory cytokines including TNF-a, IL-1ß, IL-6, INF-?, and IL-8. Accordingly, a role for IL-32 has been reported in the pathogenesis of chronic inflammatory diseases including IBD, COPD and RA. IL-32 is highly expressed in several cancer tissues, and plays a crucial role in cancer development through tumor initiation, cell proliferation, and tumor maintenance. The purified Mouse anti Human interleukin-32 antibody, clone E03-4C9 (MCA6212GA) can be used as a capture antibody in a sandwich ELISA with the biotinylated Mouse anti Human interleukin-32 antibody, clone B01-2A7 (MCA6213B) as the detection antibody.

ELISA

ELISA: 1 µg/ml

Human

E. coli derived recombinant human interleukin-32 (Cys2-Lys131).

Mouse

Monoclonal

E03-4C9

IgG1

Unconjugated

Protein G affinity chromatography of tissue culture supernatant.

Liquid

Supplied in Phosphate Buffered Saline with 0.09% Sodium Azide.

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Mouse anti Human interleukin-32 antibody, clone E03-4C9, recognizes interleukin-32 (IL-32), also known as NK4 and TAIF. IL-32 is a pro-inflammatory cytokine with roles in inflammation and immune regulation, and its expression is strongly regulated by pathogens and pro-inflammatory cytokines (Hong et al. 2017). IL-32 promotes inflammation by upregulating other inflammatory cytokines including TNF-a, IL-1ß, IL-6, INF-?, and IL-8 (Al-Shobaili et al. 2018). Accordingly, a role for IL-32 has been reported in the pathogenesis of chronic inflammatory diseases including IBD, COPD and RA (Damen et al. 2017). IL-32 is highly expressed in several cancer tissues, and plays a crucial role in cancer development through tumor initiation, cell proliferation, and tumor maintenance (Yan et al. 2018).The purified Mouse anti Human interleukin-32 antibody, clone E03-4C9 (MCA6212GA) can be used as a capture antibody in a sandwich ELISA with the biotinylated Mouse anti Human interleukin-32 antibody, clone B01-2A7 (MCA6213B) as the detection antibody.

IL 32alpha, IL 32beta, IL 32delta, IL 32gamma, IL32, IL32_HUMAN, Interleukin 32, Interleukin 32 small, Interleukin 32 theta, Interleukin-32, interleukin-32 eta, Natural killer cell transcript 4, Natural killer cells protein 4, NK 4, NK4, OTTHUMP00000236040, OTTHUMP00000236041, OTTHUMP00000236042, OTTHUMP00000236043, OTTHUMP00000236044, OTTHUMP00000236045, OTTHUMP00000236046, OTTHUMP00000236047, OTTHUMP00000236048, OTTHUMP00000236049, OTTHUMP00000236050, OTTHUMP00000236051, OTTHUMP00000236052, OTTHUMP00000236053, OTTHUMP00000236054, OTTHUMP00000241545, OTTHUMP00000241602, OTTHUMP00000241603, OTTHUMP00000241604, OTTHUMP00000241605, OTTHUMP00000241606, OTTHUMP00000241607, OTTHUMP00000241608, OTTHUMP00000241609, OTTHUMP00000241610, OTTHUMP00000241611, OTTHUMP00000241612, TAIF, TAIFa, TAIFb, TAIFc, TAIFd, Tumor necrosis factor alpha-inducing factor