This antibody recognises human interleukin-13 (IL-13), a 12.5 kDa immunoregulatory cytokine produced primarily by activated T helper type 2 (Th2) cells, and also by mast cells and NK cells. IL-13 induces the stimulation of B cell proliferation, antibody production and plays an important role in the induction of the pathophysiological features of allergic asthma, independently of Immunoglobulin E (IgE) and eosinophils.
Applicazioni
Flow Cytometry
Diluizioni consigliate
Use 10µl of the suggested working dilution to label 1x106 cells in 100µl.
Reattività
Human
Immunogeno
Recombinant human IL-13.
Specie ospite
Mouse
Clonalità
Monoclonal
Clona ID
B-P6
Isotipo
IgG1
Coniugare
FITC
Excitation: 490nm, Emission: 525nm
Purificazione
Ion exchange chromatography of ascites.
Concentrazione
Lot Specific
Forma del prodotto
Liquid
Formulazione
Supplied in TRIS Buffered Saline, 1% BSA and 0.02% Sodium Azide.
Conservazione
Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended. This product is photosensitive and should be protected from light.
Note generali
Mouse anti Human CD13 antibody, clone B-P6 recognizes human interleukin-13 (IL-13), a 12.5 kDa immunoregulatory cytokine produced primarily by activated T helper type 2 (Th2) cells, and also by mast cells and NK cells. IL-13 induces the stimulation of B cell proliferation, antibody production and plays an important role in the induction of the pathophysiological features of allergic asthma, independently of Immunoglobulin E (IgE) and eosinophils (Wills-Karp et al. 1998).