Anti-IGFBP3 Anticorpo [IGFBP3/3517] (A278249)

Anticorpo monoclonale [IGFBP3/3517] di topo contro IGFBP3 per Flow Cytometry e IF.

Alternative Formats and ConjugatesAlternative Formats

Spese di spedizione
Tempi di consegna
4-6 Giorni lavorativi
Telefono
+1 (314) 370-6046
Lun - Ven, 8:00 - 16:00 AST
E-mail
orders@antibodies.com
Nome
Anti-IGFBP3 Antibody [IGFBP3/3517] - BSA and Azide free
Descrizione
Mouse monoclonal [IGFBP3/3517] antibody to IGFBP3.
Specificità
The Insulin-like growth factor-binding proteins, or IGFBPs, are a family of homologous proteins that have co-evolved with the IGFs. They serve not only as shuttle molecules for the soluble IGFs, but also confer a level of regulation to the IGF signaling system. Physical association of the IGFBPs with IGF influences the bio-availability of the growth factors, as well as their concentration and distribution in the extracellular environment. In addition, the IGFBPs appear to have biological activity independent of the IGFs. Seven IGFBPs have thus far been described, each differing in their tissue distribution, half-lives and modulation of IGF interactions with their receptors. IGFBP3 is the most abundant IGFBP and is complexed with roughly 80% of the serum IGFs. Both IGFBP3 and IGFBP4 are released by dermal fibroblasts in response to incision injury.
Applicazioni
Flow Cytometry, IF
Diluizioni consigliate
Flow Cytometry: 1-2 µg/million cells, IF: 1-2 µg/ml
Reattività
Human
Immunogeno
Recombinant full-length human IGFBP3 protein.
Specie ospite
Mouse
Clonalità
Monoclonal
Clona ID
IGFBP3/3517
Isotipo
IgG2b
Catene leggere
kappa
Coniugare

Unconjugated

Purificazione
Protein A/G chromatography.
Concentrazione
1 mg/ml
Peso molecolare
40 kDa / 44 kDa
Forma del prodotto
Liquid
Formulazione
Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.
Conservazione
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Note generali
This monoclonal antibody is also available in a different formulation with BSA and Sodium Azide - Anti-IGFBP3 Antibody [IGFBP3/3517] (A277661).
Sinonimi
Acid stable subunit of the 140 K IGF complex, Binding protein 29, Binding protein 53, BP 53, BP53, Growth hormone dependent binding protein , IBP 3, IBP-3, IBP3, IBP3_HUMAN, IGF binding protein 3, IGF-binding protein 3, IGFBP 3, IGFBP-3, Insulin Like Growth Factor Binding Protein 3, Insulin-like growth factor binding protein 3 precursor, Insulin-like growth factor-binding protein 3
Dichiarazione di non responsabilità
Questo prodotto è solo per uso di ricerca. Non è inteso per uso diagnostico o terapeutico.

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