This antibody reacts with CD50 (ICAM-3), a 120-130 kDa type I membrane protein (immunoglobulin supergene family) expressed on leukocytes, endothelial cells and Langerhans cells; it is negative on platelets and erythrocytes. The MEM-04 blocks DC-SIGN (CD209) binding to ICAM-3 (epitope in D1).
Applicazioni
Flow Cytometry, IHC-P, Functional Studies
Diluizioni consigliate
FUNC: This antibody blocks DC-SIGN (CD209) binding to ICAM-3 (epitope in D1), Flow Cytometry: 1-4 µg/ml, IHC-P: 10 µg/ml; Positive Control: tonsil.
Reattività
Human
Immunogeno
Leukocytes from a patient suffering from a LGL Type leukemia.
Specie ospite
Mouse
Clonalità
Monoclonal
Clona ID
MEM-04
Isotipo
IgG2b
Catene leggere
kappa
Coniugare
Unconjugated
Purificazione
Protein A chromatography.
Concentrazione
1 mg/ml
MW previsto
120-130 kDa
Forma del prodotto
Liquid
Formulazione
Supplied in Phosphate Buffered Saline, pH 7.4, without Sodium Azide (0.2 µm filter sterilized). Endotoxin level is less than 0.01 EU/µg of the protein.
Conservazione
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze/thaw cycles.