Anti-HSP60 Anticorpo [LK1] (A248883)

Anti-HSP60 Antibody [LK1]

Mouse monoclonal [LK1] antibody to HSP60.

This antibody recognizes a 60kDa protein, identified as the heat shock protein 60 (hsp60). Its epitope is localized between aa 383-447 of human hsp60. A wide variety of environmental and pathophysiological stressful conditions trigger the synthesis of a family of proteins known as heat shock proteins (hsp s), more appropriately called as stress response proteins (srp s). Hsp60 is a potential antigen in a number of autoimmune diseases. In human arthritis and in experimentally induced arthritis in animals, disease development coincides with the development of immune reactivity directed against not only bacterial hsp60, but also against its mammalian homolog.

Flow Cytometry, IF, WB, IHC-P

Flow Cytometry: 1-2 µg/million cells, IF: 1-2 µg/ml, WB: 0.25-0.5 µg/ml, IHC-P: 1-2 µg/ml

Human, Mouse, Rat, Hamster, Sheep, Rabbit, Bovine, Canine, Porcine, Monkey, Chicken, Xenopus laevis, Drosophila

This antibody does not cross react with bacteria, helminths, or spinach.

Recombinant human HSP60 protein.

Mouse

Monoclonal

LK1

IgG1

kappa

Protein A/G chromatography.

200 µg/ml

60 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-HSP60 Antibody [LK1] - BSA and Azide free (A252063).

60 kDa chaperonin, 60 kDa heat shock protein, mitochondrial, CH60_HUMAN, Chaperonin, Chaperonin 60, Chaperonin, 60-KD, CPN60, fa04a05, GROEL, Heat shock 60kDa protein 1, heat shock 60kDa protein 1 (chaperonin), Heat shock protein 1 (chaperonin), Heat shock protein 60, Heat shock protein 65, heat shock protein family D (Hsp60) member 1, HLD4, Hsp 60, HSP 65, HSP-60, HSP65, HSPD1, HuCHA60, Mitochondrial matrix protein P1, P60 lymphocyte protein, short heat shock protein 60 Hsp60s1, SPG13