Anti-HLA Class 1 ABC Anticorpo [Bra-23/9] (A316468)

$765

Anticorpo monoclonale [Bra-23/9] di topo contro HLA Class 1 ABC per Flow Cytometry e IF.

Alternative Formats and ConjugatesAlternative Formats

Spese di spedizione
Tempi di consegna
4-6 Giorni lavorativi
Telefono
+1 (314) 370-6046
Lun - Ven, 8:00 - 16:00 AST
E-mail
orders@antibodies.com
Nome
Anti-HLA Class 1 ABC Antibody [Bra-23/9] - BSA and Azide free
Descrizione
Mouse monoclonal [Bra-23/9] antibody to HLA Class 1 ABC.
Specificità
Reacts with a monomorphic determinant of human major histocompatibility (MHC) class I antigens (HLA-A, B and C). Immunoprecipitation of lactoperoxidase radioiodinated cell surface proteins and surface sialoglycoproteins radiolabeled by sodium metaperiodate/tritiated sodium borohydride technique confirmed the structure gp44,p12 (consisting of a 44kDa glycopeptide linked with a non-glycosylated 12kDa peptide) typical for MHC class I antigen(s) as a structure recognized by Bra23/9. Human MHC class I antigens are expressed constitutively on all nucleated cells lymphocytes such as lymphocytes, thymocytes, granulocytes, and bone marrow cells and are absent on erythrocytes. MHC class I antigens play a role in class I MHC-associated antigen presentation, inhibition of NK cell cytotoxicity, tumor surveillance, and tissue allotransplantation.
Applicazioni
Flow Cytometry, IF
Controllo positivo
THP-1 and Jurkat cells. Tonsil or lymph node.
Diluizioni consigliate
Flow Cytometry: 1-2 µg/million cells, IF: 1-2 µg/ml
Reattività
Human, Mouse, Non-Human Primates
Immunogeno
Human REH cells (pre-B leukaemia cell line).
Specie ospite
Mouse
Clonalità
Monoclonal
Clona ID
Bra-23/9
Isotipo
IgG2a
Catene leggere
kappa
Coniugare

Unconjugated

Purificazione
Protein A/G chromatography.
Concentrazione
1 mg/ml
Peso molecolare
~41 kDa
Forma del prodotto
Liquid
Formulazione
Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.
Conservazione
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Sinonimi
HLA A, HLA B, HLA C, HLA class 1 A, HLA class 1 B, HLA class 1 C, Major histocompatibility complex, class I, A + B + C, MHC class I HLA A, MHC class I HLA B, MHC class I HLA C, MHC HLA ABC
Dichiarazione di non responsabilità
Questo prodotto è solo per uso di ricerca. Non è inteso per uso diagnostico o terapeutico.

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