Specificità
This antibody recognises Histone deacetylase 5, also known as HDAC5. Histone deacetylases are chromatin-modifying enzymes that are involved in regulation of many aspects of cell biology including tissue differentiation, autophagy, apoptosis, migration, mitosis and angiogenesis. HDAC5 is a member of class IIa of the histone deacetylases which unlike class I is not found in the only in the nucleus but rather shuttles back and forth between nucleus and cytoplasm.