This antibody recognises Histone deacetylase 4, also known as HDAC4. Histone deacetylases are chromatin-modifying enzymes that are involved in regulation of many aspects of cell biology including tissue differentiation, autophagy, apoptosis, migration, mitosis and angiogenesis. HDAC4 is a member of class IIa of the histone deacetylases which unlike class I is not found in the only in the nucleus but rather shuttles back and forth between nucleus and cytoplasm.
Applicazioni
WB, IF
Diluizioni consigliate
IF: 1:50 - 1:200, WB: 1:500 - 1:2,000
Reattività
Human, Mouse, Rat
Immunogeno
Synthetic peptide of human HDAC4.
Specie ospite
Rabbit
Clonalità
Polyclonal
Isotipo
IgG
Coniugare
Unconjugated
Concentrazione
Lot Specific
Peso molecolare
Approximately 119 kDa in cell lysates and tissue lysates under reducing conditions
Forma del prodotto
Liquid
Formulazione
Supplied in Phosphate Buffered Saline with 50% Glycerol and 0.02% Sodium Azide.
Conservazione
Store undiluted at -20°C. Storage in frost free freezers is not recommended. Avoid freeze-thaw cycles. Should this product contain a precipitate we recommend microcentrifugation before use.
Note generali
Rabbit anti histone deacetylase 4 antibody recognizes histone deacetylase 4, also known as HDAC4. Histone deacetylases are chromatin-modifying enzymes that are involved in regulation of many aspects of cell biology including tissue differentiation, autophagy, apoptosis, migration, mitosis and angiogenesis. HDAC4 is a member of class IIa of the histone deacetylases which unlike class I is not found in the only in the nucleus but rather shuttles back and forth between nucleus and cytoplasm.
Sinonimi
AHO3, BDMR, EC 3.5.1.98, HA6116, HD 4, HD4, HDAC 4, HDAC A, HDAC4_HUMAN, HDACA, Histone deacetylase 4, Histone Deacetylase A, KIAA0288