Ricombinante Anti-Granzyme B Anticorpo [GZMB/4539R] (A277995)

Anticorpo monoclonale [GZMB/4539R] di coniglio contro Granzyme B per WB e IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Spese di spedizione
Tempi di consegna
4-6 Giorni lavorativi
Telefono
+1 (314) 370-6046
Lun - Ven, 8:00 - 16:00 AST
E-mail
orders@antibodies.com
Nome
Anti-Granzyme B Antibody [GZMB/4539R]
Descrizione
Recombinant rabbit monoclonal [GZMB/4539R] antibody to Granzyme B.
Specificità
Granzyme B is a member of the granule serine protease family stored specifically in NK cells or cytotoxic T cells. Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. Granzyme B is crucial for the rapid induction of target cell apoptosis by CTLs in the cell-mediated immune response. Granzyme B is useful as a marker in the identification of NK/T-cell lymphomas. High percentages of cytotoxic T-cells have been shown to be an unfavorable prognostic indicator in Hodgkin s Disease.
Applicazioni
WB, IHC-P
Diluizioni consigliate
WB: 2-4 µg/ml, IHC-P: 1-2 µg/ml
Reattività
Human
Immunogeno
Recombinant fragment, around amino acids 73-187, of human Granzyme B protein. The exact sequence is proprietary.
Specie ospite
Rabbit
Clonalità
Monoclonal
Clona ID
GZMB/4539R
Isotipo
IgG
Coniugare

Unconjugated

Purificazione
Protein A/G chromatography.
Concentrazione
200 µg/ml
Peso molecolare
29-32 kDa
Forma del prodotto
Liquid
Formulazione
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Conservazione
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Note generali
This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-Granzyme B Antibody [GZMB/4539R] - BSA and Azide free (A278583).
Sinonimi
C11, Cathepsin G like 1, Cathepsin G-like 1, CCPI, CGL 1, CGL1, CSP B, CSPB, CTLA-1, CTLA1, CTSGL1, Cytotoxic serine protease B, Cytotoxic T lymphocyte associated serine esterase 1, Cytotoxic T lymphocyte proteinase 2, Cytotoxic T-lymphocyte proteinase 2, Fragmentin 2, Fragmentin-2, GRAB_HUMAN, Granzyme 2, Granzyme B (granzyme 2, cytotoxic T lymphocyte associated serine esterase 1), Granzyme-2, GranzymeB, GRB, Gzmb, Hlp, Human lymphocyte protein, Lymphocyte protease, Protease, serine, B, SECT, T cell serine protease 1-3E, T-cell serine protease 1-3E
Dichiarazione di non responsabilità
Questo prodotto è solo per uso di ricerca. Non è inteso per uso diagnostico o terapeutico.

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