This antibody recognises C-X-C motif chemokine 6 (CXCL6) also known as chemokine alpha 3, granulocyte chemotactic protein 2 and small inducible cytokine B6. CXCL6 is a member of the ELR+ CXC family of chemokines. It is a potent pro-inflammatory neutrophil chemoattractant which can elicit ultrastructural changes and activate pathways that define neutrophil phenotype and function (Mittal et al. 2008, Linge et al. 2008). It achieves this through the regulation of downstream pathways via its receptors CXCR1 and CXCR2.

Applicazioni

WB, ELISA

Diluizioni consigliate

ELISA: 0.5 µg/ml - 2.0 µg/ml, WB: 0.1 µg/ml - 0.2 µg/ml

Reattività

Human

Immunogeno

E. coli derived full length recombinant human CXCL6.

Specie ospite

Rabbit

Clonalità

Polyclonal

Isotipo

IgG

Coniugare

Unconjugated

Concentrazione

1 mg/ml after reconstitution.

Forma del prodotto

Lyophilized

Ricostituzione

Reconstitute with 0.1 ml of distilled water.

Formulazione

Supplied in Phosphate Buffered Saline.

Conservazione

Lyophilized: Store at -20°C. Reconstituted: Store undiluted at -20°C, avoid freeze / thaw cycles. Storage in frost free freezers is not recommended. Should this product contain a precipitate we recommend microcentrifugation before use.

Note generali

Mouse anti Human CXCL6 antibody, recognizes C-X-C motif chemokine 6 (CXCL6) also known as chemokine alpha 3, granulocyte chemotactic protein 2 and small inducible cytokine B6. CXCL6 is a member of the ELR+ CXC family of chemokines. It is a potent pro-inflammatory neutrophil chemoattractant which can elicit ultrastructural changes and activate pathways that define neutrophil phenotype and function (Mittal et al. 2008, Linge et al. 2008). It achieves this through the regulation of downstream pathways via its receptors CXCR1 and CXCR2 (Lui et al. 2019).

Sinonimi

C X C motif chemokine 6, Chemokine (C X C motif) ligand 6, Chemokine alpha 3, CKA 3, CKA-3, CKA3, CXCL 6, CXCL6, CXCL6_HUMAN, GCP 2, GCP-2, Granulocyte chemotactic protein 2, N-processed variant 3, SCYB6, Small inducible cytokine B6, Small inducible cytokine subfamily B (Cys X Cys) member 6, Small inducible cytokine subfamily B (Cys X Cys) member b, Small-inducible cytokine B6

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Secondari adatti

Dichiarazione di non responsabilità

Questo prodotto è solo per uso di ricerca. Non è inteso per uso diagnostico o terapeutico.