Anti-GCET2 Anticorpo [HGAL/2373] (A278209)

Anticorpo monoclonale [HGAL/2373] di topo contro GCET2 per IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Spese di spedizione
Tempi di consegna
4-6 Giorni lavorativi
Telefono
+1 (314) 370-6046
Lun - Ven, 8:00 - 16:00 AST
E-mail
orders@antibodies.com
Nome
Anti-GCET2 Antibody [HGAL/2373] - BSA and Azide free
Descrizione
Mouse monoclonal [HGAL/2373] antibody to GCET2.
Specificità
This antibody recognizes a protein of kDa, which is identified as HGAL. It contains a putative PDZ-interacting domain, an immunoreceptor tyrosine-based activation motif (ITAM), and two putative SH2 binding sites. In B cells, its expression is specifically induced by interleukin-4. HGAL is specifically expressed in germinal center B-cells, but is absent in mantle and marginal zone B-cells and in the inter-follicular and para-cortical regions in normal tonsils and lymph nodes. Its high degree of specificity for germinal center B-cells makes anti-HGAL an ideal marker for the detection of germinal center-derived B-cell lymphomas. HGAL expression has been used to help elucidate nodal marginal zone lymphoma (NMZL) from cases of diffuse follicle center lymphoma. Additionally, HGAL expression was shown to correlate with survival in patients with diffuse large B-cell lymphoma (DLBCL).
Applicazioni
IHC-P
Diluizioni consigliate
IHC-P: 1-2 µg/ml
Reattività
Human
Immunogeno
Recombinant fragment, around amino acids 1-200, of human GCET2 protein. The exact sequence is proprietary.
Specie ospite
Mouse
Clonalità
Monoclonal
Clona ID
HGAL/2373
Isotipo
IgG2b
Catene leggere
kappa
Coniugare

Unconjugated

Purificazione
Protein A/G chromatography.
Concentrazione
1 mg/ml
Peso molecolare
21 kDa
Forma del prodotto
Liquid
Formulazione
Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.
Conservazione
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Note generali
This monoclonal antibody is also available in a different formulation with BSA and Sodium Azide - Anti-GCET2 Antibody [HGAL/2373] (A277621).
Sinonimi
GCAT2, Gcet, GCET2 germinal center expressed transcript 2, GCET2 germinal centre expressed transcript 2, Gcsam, GCSAM_HUMAN, Germinal center associated lymphoma, Germinal center associated lymphoma protein, Germinal center B cell associated protein 2, Germinal center B-cell-expressed transcript 2 protein, Germinal center expressed transcript 2, Germinal center-associated lymphoma protein, Germinal center-associated signaling and motility protein, Germinal centre associated lymphoma, Germinal centre associated lymphoma protein, Germinal centre B cell associated protein 2, Germinal centre expressed transcript 2, hGAL, M17, M17 L
Dichiarazione di non responsabilità
Questo prodotto è solo per uso di ricerca. Non è inteso per uso diagnostico o terapeutico.

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