Anti-GATA4 Anticorpo [PCRP-GATA4-1A7] (A316379)

$765

Anticorpo monoclonale [PCRP-GATA4-1A7] di topo contro GATA4 per Flow Cytometry.

Alternative Formats and ConjugatesAlternative Formats

Spese di spedizione
Tempi di consegna
4-6 Giorni lavorativi
Telefono
+1 (314) 370-6046
Lun - Ven, 8:00 - 16:00 AST
E-mail
orders@antibodies.com
Nome
Anti-GATA4 Antibody [PCRP-GATA4-1A7] - BSA and Azide free
Descrizione
Mouse monoclonal [PCRP-GATA4-1A7] antibody to GATA4.
Specificità
Members of the GATA family share a conserved zinc finger DNA-binding domain and are capable of binding the WGATAR consensus sequence. GATA-1 is erythroid-specific and is responsible for the regulated transcription of erythroid genes. It is an essential component in the generation of the erythroid lineage. GATA-2 is expressed in embryonic brain and liver, HeLa and endothelial cells, as well as erythroid cells. Studies with a modified GATA consensus sequence, AGATCTTA, have shown that GATA-2 and GATA-3 recognize this mutated consensus while GATA-1 has poor recognition of this sequence. This indicates broader regulatory capabilities of GATA-2 and GATA-3 than GATA-1. GATA-3 is highly expressed in T lymphocytes. GATA-4, GATA-5 and GATA-6 comprise a subfamily of transcription factors. GATA-4 and GATA-6 are found in heart, pancreas and ovary; lung and liver tissues exhibit GATA-6, but not GATA-4, expression. GATA-5 expression has been observed in differentiated heart and gut tissues and is present throughout the course of development in the heart. Although expression patterns of the various GATA transcription factors may overlap, it is not yet apparent how the GATA factors are able to discriminate in binding their appropriate target sites.
Applicazioni
Flow Cytometry
Controllo positivo
HeLa or MCF-7 cells.
Diluizioni consigliate
Flow Cytometry: 1-2 µg/million cells
Reattività
Human
Immunogeno
Recombinant fragment (around Amino Acids 262-321) of human GATA4 protein.
Specie ospite
Mouse
Clonalità
Monoclonal
Clona ID
PCRP-GATA4-1A7
Isotipo
IgG2b
Coniugare

Unconjugated

Purificazione
Protein A/G chromatography.
Concentrazione
1 mg/ml
Peso molecolare
44.57 kDa
Forma del prodotto
Liquid
Formulazione
Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.
Conservazione
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Sinonimi
ASD2, GATA 4, GATA binding protein 4, GATA-binding factor 4, GATA4_HUMAN, MGC126629, Transcription factor GATA 4, Transcription factor GATA-4, Transcription factor GATA4, VSD1
Dichiarazione di non responsabilità
Questo prodotto è solo per uso di ricerca. Non è inteso per uso diagnostico o terapeutico.

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