Anti-GAP43 Anticorpo (A283902)

Anti-GAP43 Antibody

Rabbit polyclonal antibody to GAP43.

This antibody recognises the protein designated GAP43, a neuronal protein that is expressed at elevated levels during development and also during regenerative axon growth.GAP43 (also known as neuromodulin, pp46, B-50, Protein F1 and calmodulin-binding protein P-57) is a protein of approximately 25 kDa that migrates on SDS-PAGE gels with an apparent size of 40-50 kDa. The aberrant migration is due to the unusually low abundance of hydrophobic amino acid residues. GAP43 is found tightly associated with neuronal membranes due to palmitoylation. The solubilised protein binds calmodulin, although this is reduced following protein kinase C phosphorylation of GAP43.

WB, IHC-P, IHC-Fr, IF, IP

WB: 1:500 - 1:1,000

Feline, Human, Rat, Monkey, Mouse

Purified GAP43 from cat brain.

Rabbit

Polyclonal

IgG

Unconjugated

Lot Specific

Liquid

Supplied as serum with <0.1% Sodium Azide.

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Rabbit anti GAP43 antibody recognises the protein designated GAP43, a neuronal protein that is expressed at elevated levels during development and also during regenerative axon growth.GAP43 (also known as neuromodulin, pp46, B-50, Protein F1 and calmodulin-binding protein P-57) is a protein of approximately 25 kDa that migrates on SDS-PAGE gels with an apparent size of 40-50 kDa. The aberrant migration is due to the unusually low abundance of hydrophobic amino acid residues. GAP43 is found tightly associated with neuronal membranes due to palmitoylation. The solubilised protein binds calmodulin, although this is reduced following protein kinase C phosphorylation of GAP43.

Axonal membrane protein GAP 43, Axonal membrane protein GAP-43, B 50, Calmodulin binding protein P 57, F1, GAP 43, Growth Associated Protein 43, Growth-associated protein 43, Nerve Growth Related Peptide, Nerve growth related peptide GAP43, NEUM_HUMAN, Neural phosphoprotein B 50, Neural phosphoprotein B-50, Neuromodulin, Neuron growth associated protein 43, PP46, Protein F1, QtrA-11580, QtrA-13071