Anti-Flt3 Ligand / Flt3L Anticorpo (A283919)

Anti-Flt3 Ligand / Flt3L Antibody - BSA and Azide free

Rabbit polyclonal antibody to Flt3 Ligand / Flt3L.

This antibody recognises the ubiquitously expressed human growth factor Flt3-Ligand (Flt3L), a 235aa type I transmembrane glycoprotein which regulates the proliferation of early haematopoietic cells.Flt3L exists in both a membrane-bound and proteolytically cleaved soluble isoform, both of which are biologically active, and initiates cell proliferation/ differentiation signalling in co-operation with other colony stimulating factors (CSFs) and interleukins, by binding to and activating the tyrosine kinase receptor Flt3 (FLT3R), expressed highly by hematopoietic progenitor cells and stem cells.

WB, ELISA, Functional Assays

ELISA: 0.5 µg/ml, Functional Assays: 0.25 - 0.75 µg/ml, WB: 0.1 - 0.2 µg/ml

Human

Recombinant human Flt3-Ligand.

Rabbit

Polyclonal

IgG

Unconjugated

Lyophilized

Reconstitute with 0.1 ml of distilled water. For long term storage the addition of 0.09% sodium azide is recommended. For functional studies do not add sodium azide.

Supplied in Phosphate Buffered Saline.

Lyophilized: Store at -20°C. Reconstituted: Store undiluted at -20°C, avoid freeze / thaw cycles. Storage in frost free freezers is not recommended. Should this product contain a precipitate we recommend microcentrifugation before use.

Rabbit anti Human Flt3 Ligand antibody recognizes the ubiquitously expressed human growth factor Flt3-Ligand (Flt3L), a 235aa type I transmembrane glycoprotein which regulates the proliferation of early haematopoietic cells.Flt3L exists in both a membrane-bound and proteolytically cleaved soluble isoform, both of which are biologically active, and initiates cell proliferation/ differentiation signalling in co-operation with other colony stimulating factors (CSFs) and interleukins, by binding to and activating the tyrosine kinase receptor Flt3 (FLT3R), expressed highly by hematopoietic progenitor cells and stem cells.