This antibody recognises the ~55 kDa FLIPL protein, a FLICE inhibitory protein.FLIP was cloned independently in a number of laboratories, and is also known as Casper, I-FLICE, FLAME-1, CASH and CLARP. FLIP has two death effector domains (DEDs) and a caspase-like domain. It interacts with FADD and caspase-8 and -10, potently inhibiting apoptosis by all known death receptors.FLIP exists in a short form (FLIPS) and a long form (FLIPL). Only FLIPL is recognised by Rabbit anti Human FLIP L antibody (AHP430).

Applicazioni

WB, IHC-Fr

Diluizioni consigliate

WB: 1:500 - 1:2,000

Reattività

Human

Immunogeno

A peptide corresponding to a region at the C-terminus of human FLIPL.

Specie ospite

Rabbit

Clonalità

Polyclonal

Isotipo

IgG

Coniugare

Unconjugated

Concentrazione

1 mg/ml

Forma del prodotto

Liquid

Formulazione

Supplied in Phosphate Buffered Saline with 0.02% Sodium Azide.

Conservazione

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Note generali

Rabbit anti Human FLIP L antibody recognizes the ~55 kDa FLIPL protein, a FLICE inhibitory protein.FLIP was cloned independently in a number of laboratories, and is also known as Casper, I-FLICE, FLAME-1, CASH and CLARP. FLIP has two death effector domains (DEDs) and a caspase-like domain. It interacts with FADD and caspase-8 and -10, potently inhibiting apoptosis by all known death receptors.FLIP exists in a short form (FLIPS) and a long form (FLIPL). Only FLIPL is recognised by Rabbit anti Human FLIP L antibody (AHP430).

Sinonimi

c FLIP, c FLIPL, c FLIPR, c FLIPS, c-FLIP, c-FLIPL, c-FLIPR, c-FLIPS, CASH, CASP8 and FADD like apoptosis regulator, CASP8 and FADD-like apoptosis regulator subunit p12, CASP8AP1, Caspase homolog, Caspase like apoptosis regulatory protein, Caspase related inducer of apoptosis, Caspase-eight-related protein, Caspase-like apoptosis regulatory protein, Casper, Cellular FLICE-like inhibitory protein, CFLA, Cflar, CFLAR_HUMAN, CLARP, FADD like anti apoptotic molecule, FADD-like antiapoptotic molecule 1, FLAME, FLAME-1, FLAME1, I FLICE, I-FLICE, Inhibitor of FLICE, MACH-related inducer of toxicity, MRIT, OTTHUMP00000163715, OTTHUMP00000206475, OTTHUMP00000206476, OTTHUMP00000206478, OTTHUMP00000206479, OTTHUMP00000206480, OTTHUMP00000206482, OTTHUMP00000207360, Usurpin, Usurpin beta

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Secondari adatti

Dichiarazione di non responsabilità

Questo prodotto è solo per uso di ricerca. Non è inteso per uso diagnostico o terapeutico.